A molecular structure located on the surface of the cell that binds with a particular chemical or chemicals.
Receptor
100
A general term referring to a large number of cells, all of which are similar, on which a particular drug is intended to act.
Target Cell
100
Any substance produced by the metabolic process.
Metabolite
100
The degree to which a drug becomes available to body tissue after administration.
Bioavailability
100
Approximately ____ _________ Americans are addicted to alcohol.
14 million
200
The study of biochemical and physiologic effects of drugs and their mechanism of action.
pharmacodynamics
200
An interaction between 2 or more drugs administered to a patient, resulting in either an increase or a decrease in the therapeutic effects of one or more of the drugs, or adverse effect.
drug-drug interaction
200
The study of the time course of a drug and its metabolites in the body following drug administration.
Pharmacokinetics
200
The time it takes a drug to be eliminated from the body.
Clearance
200
Alcohol contributes to more than ______ deaths per year.
100,000
300
The location where a drug will exert its effect.
Site of action
300
The time required for serum concentration levels of absorbed and distributed drug to decrease by one-half.
Half-life
300
The process by which drugs are eliminated from the body.
Excretion
300
A pattern of compulsive substance abuse characterized by continued psychological and physiological craving or need for the substance and its effects.
Addiction
300
Which drug is used in management of enforced sobriety?
Antabuse
400
A type of drug that activates the receptor to produce a predicted action.
Agonist
400
A measurement of the strength of a drug that is required to produce a specific effect on the body.
Potency
400
The process by which a drug is moved from the site of administration into the bloodstream.
Absorption
400
When a person requires larger doses of a drug to achieve the same effect.
Tolerance
400
Name at least 2 BZD drugs used for alcohol withdrawal.
Ativan, Librium, Serax, Valium
500
The type of drug that prevents receptor activation.
Antagonist
500
A measurement of the specific amount of a drug that will achieve 50% of the maximal response.
ED50
500
The process by which an absorbed drug is moved from the bloodstream to body tissues or receptors.
Distribution
500
The state of being dependent.
Dependency
500
Drinking alcohol with alprazolam can cause problems such as:
Drowsiness, dizziness, an increased risk of overdose