You Take Medicine Now
Buprenorphine and Codeine are examples of drugs in this schedule class
Class III
What is the minimum age a child must be in order for long acting bronchodialators to be indicated?
At least 6 years old
What drug class used to treat cystic fibrosis targets the underlying condition and not just the symptoms caused
BONUS 100: what is the suffix that all drugs in this class share?
CFTR modulators
BONUS: -caftor
The mechanism of action employed by this class of anti-fungals is overall fungistatic by blocking fungal CYP450 which in turn alters the permeability of the cell wall
Imidazoles
Maintance for all individuals with psoriasis shoud include the use of what two classes of drug?
topical low-potency steroid + vitamin D analog
There are two rules that apply to decimal zeros when writing prescriptions. What are they?
NO TRAILING ZEROS 5.0X -> 5 :)
ALWAYS USE LEADING ZERO .5X ->0.5 :)
What is the difference between use of an ICS in patients with Asthma vs COPD?
ICS is not automatically indicated for COPD
What are the four RIPE drugs given in the first portion of active TB infection
Rifampin, Isoniazid, Pyrazinamide, Ethambutol
Vitamin D analogues can be combined with what other agent to improve overall outcome?
TCS
An emollient: shea butter, palm oil, lipids & oils
What are the four things to include when writing a complete sig
Dose, Route, Frequency, Duration/Indication
What is a serious side effect of Leukotriene Receptor Antagonists that requires close supervision of the individual taking it?
BONUS 100: give me an example of agents within this class
BONUS: Montelukast(Singulair) & zafirlukast(Accolate)
What drug is often used prophylactically for altitude sickness in order to increase respiratory drive?
Carbonic Anhydrase Inhibitors ie. Acetazolamide
This phototoxic plant compound is used in combination with UVA light therapy to treat sever Psoriasis
BONUS 100: this treatment increases the risk of what condition?
Psoralens
BONUS: nonmelanoma skin cancer
medium-high potency steroid + a biologic/systemic JAK inhibitor
James LeDookieschmit messages you for another refill for his amphetamine-dextroamphetamine prescription. What are the federal refill rules for medications of this class
Up to five refills within 6 months
DAILY DOUBLE!!
Identify the four biologic classes used to treat asthma
BONUS 100: Name at least one agent in each class
IgE inhibitor: Xolair(omalizumab)
IL-5 inhibitor: Nucala(mepolizumab), Cinqair(reslizumab)
IL-4a receptor antagonist: Dupixent(dupilumab)
IL-5/13 monoclonal antibody inhibitor: Fasenra(Benralizumab)
Which drug class is often combined with a PDE-5 inhibitor for treatment in group 1 Pulmonary Arterial Hypertension
BONUS 100: Identify at least one drug in each class
Endothelin Receptor Agonists(ERAs): ambrisentan, bosentan, macitentan
PDE-5: sildenafil, tadalafil
Name one of three Topical Retinoid agents discussed in the slides:
BONUS 100: These agents are derivatives of what molecule
Tazarotene, Tretinoin, Adapalene
BONUS: Vitamin A
What anti-pruritic causes many anti-cholinergic effects and must be used with caution?
BONUS 100: what conditions would contraindicate use of this agent?
Doxepin hydrochloride 5%
BONUS: closed anngle glaucoma, sjrogens, urinary retention
What are some examples of schedule V drugs?
Pregabalin, Diphenoxylate/atropine
Grandpa Charles comes into your ED once again having his bimonthly COPD exacerbation. What is the first line pharmacologic treatment for this condition
SABA +ICS
What is the dosing regimen for the nicotine patch for an individual who smokes 12 cigarettes/day
BONUS 100: what is the NRT thats known to cause vivid night terrors?
14mg/day then step down to 7mg/day
BONUS: Varenicline(Chantix)
This agent is one of the Class I corticosteroids meaning it is the most potent formulation
BONUS 100: What common corticosteroid is in Class VII?
Clobetasol proprionate 0.05%
BONUS: Hydrocortisone 1, 2.5%
Acitretin is highly contraindicated with alcohol use. Describe the mechanism and reasoning behind this
Alcohol converts acitretin into active form etretinate which stays in the body for an extended amount of time->greatly increases teratogenic risk