This is the strongest type of chemical drug bond
covalent
Opioids primarily exert their mechanism of action on this area of the spinal cord lamina
Substantia gelatinosa
This anticholinergic has the least potential to increase heart rate
scopolamine
Suggamadex is classified as this type of agent
selective relaxant binding agent
This type of function is generally the last lost during onset of local anesthetic blockade
motor function
This opioid has been shown to display local anesthetic properties
plasma cholinesterase
Direct CNS excitation of this opioids metabolite can produce seizure activity
Meperidine
This anticholinergic agent does not cross the blood brain barrier
glycopyrolate
pKa close to pH of environment placed in
Stimulation of this nucleus sends a parasympathetic signal down the ciliary ganglion to result in miosis
Edinger Westphal
Sugammadex works on neuromuscular blockers with this type of nuclei makeup
steroidal
This is the amount that was originally given if 15 mg of a drug eliminated by first order kinetics remained after 4 half lives
240 mg
Serotonin syndrome and its associated symptoms may occur in patients taking MAOIs when combined with this opioid medication
Meperidine
This muscle/muscle group is generally the first to recover following neuromuscular blockade
diaphragm
These three locals are said to have the greatest degree of vasoconstrictive properties
Cocaine, lidocaine, ropivacaine
When binding of an agonist produces a decreased response, this is said to have occurred
desensitization
Of the agents enflurane, halothane, sevoflurane, and desflurane, this one is metabolized to the greatest degree
Halothane
EMLA cream contains these two local anesthetics
lidocaine and prilocaine
If this factor in a drugs pharmacokinetics increased, it would have an increased duration of action, less free drug, and a higher plasma concentration.
protein binding
Excitatory movements sometimes seen with propofol and etomidate are the result of this mechanism
disinhibition of subcortical centers
30 mg of toradol has the same analgesic potency as this dose of morphine
According to OSHA, healthcare personnel should not be exposed to more than this many ppm of N2O if a halogenated agent is also used?
0.5
This is the plasma concentration at which half of a drugs maximal effect is seen
EC50
The same analgesic equivalency of 100 mcg of sufentanil can be achieved with this dose of demerol
1 gram