What are anti-platelets, thrombolytics, and anti-coagulants?
I am inner ear damage that effects the vestibular system.
What is ototoxic?
What do thrombolytics (fibrinolytic) do?
What is facilitate conversion of plasminogen to plasmin for clot dissolution?
tPa, TNKase, Retevase
-ase = thrombolytic
I am the four-step process of pharmacokinetics.
What is absorption, distribution, metabolize, and excretion.
It takes _-_ half-lives to achieve steady state.
What is 4-5 half-lives?
What 5 classifications of drugs are considered to treat hypertension?
What are diuretics, sympatholytic, vasodilators, RAAS, and calcium channel blockers?
Describes the time around surgery.
What is perioperative?
Most frequently used diuretic for HTN***
Lipid-soluble molecules and small H20-soluble molecules may be passive diffusion but I am required for active transport across a barrier.
What is a carrier protein? (absorption stage)
A patient requires medication A BID and medication B TID.
What do the abbreviations stand for?
What 3 classifications of drugs decrease myocardial oxygen demand?
What are B-adrenergic blockers, calcium channel blockers, and nitrates?
This medication should be administered after a meal.
What do ACE inhibitors do and what are their side effects?
What is regulated vascular tone and sodium/water in the body. Inhibits the enzyme that converts angiotensin I to angiotensin II, blocking the breakdown of bradykinin thus vasodilation.
Associated with decreased mortality and morbidity.
Side effects: *Cough, hypotension, anemia
I slow absorption and can be taken less frequently.
What is sustained release?
We are factors that affect pharmacokinetics.
What is disease, age, genetics, gender, body composition, diet, other chemicals and physiological factors?
What classifications of drugs are anti-anginal?
This substance can change the force of the hearts contraction, either increasing or decreasing the force of it.
What is an inotrope?
These drugs decrease the automaticity of the heart.
What are sodium channel blockers, beta blockers, potassium channel blockers, and calcium channel blockers?
These four things affect the bioavailability of a drug.
What is tissue permeability, blood flow, protein binding, and storage of the drug?
A patient's BP reads 136/78 mmHg, what category do they fall in per the guidelines?
What its high blood pressure stage one?
Systolic 130-139 OR Diastolic 80-89
What classifications of drugs are anti-hyperlipidemic?
Intramuscular, intravenous, intracoronary, intrathecal, intraarticular, subcutaneous, inhalation, topical and transdermal are all considered a _____ route of absorption.
What is parenteral?
This classification of drug shows significant decrease in risk of CV death and hospitalization in patients with HF. Both patients with preserved ejection fraction and those with reduced may benefit.
Half-life of drug A is 2 hours.
Half-life of drug B is 4 hours.
In 8 hours, how much of each drug is present in the body and what one will be present longer?
Drug A is 6.25% in the body.
Drug B is 25% in the body. Thus, this will be present longer in the body.
I have affinity and efficacy but my competitor only has affinity.
What is agonists and antagonist?