Aerosol Therapy
Describing particles of different sizes.
What is heterodisperse?
The route of administration “besides the intestine”.
What is an injection (parenteral)?
Solute (g)/ total amount (mL)
% Strength
What are adrenergic bronchodilators?
An agent that blocks parasympathetic nerve fibers, allowing relaxation of the smooth muscle in the airway.
What is an anticholinergic or antimuscarinic bronchodilator?
The suspension of liquid or solid particles in a carrier gas.
What is an aerosol?
Absorption, Distribution, Metabolism, Elimination.
What is the Pharmacokinetic phase?
Total mL in a tablespoon (Tb)
15 mL
Producing effects similar to those of the sympathetic nervous system.
What is sympathomimetic?
Blocking parasympathetic nervous fibers.
What is parasympatholytic?
The process of particles settling out of suspension to remain in the lung.
What is deposition?
Aqueous Diffusion (use of channels), and Lipid Diffusion.
What is passive diffusion?
MD orders 20 g medication p.o . Pharmacy dispenses 10 g/15 mL. How many mL will you administer?
30 mL
The receptors preference for ultra-short acting adrenergic bronchodilators.
What are alpa 1&2 and Beta 1&2?
This short acting muscarinic antagonist is a nonselective anticholinergic bronchodilator.
What is ipratropium bromide?
Another word for sedimentation.
What is gravitational settling?
The proportion of a drug that reaches the systemic circulation.
What is bioavailability?
MD orders 2 g medication p.o, TID. Pharmacy dispenses 500 mg/ 2.5 mL. How many mL do you administer per day?
30 mL
This medication is available in 2.5 mg/3mL (0.083%) or 2.5/0.5 mL (0.5%) for SVN or 90 mcg/puff x 2 puff/dose.
What is albuterol sulfate?
This muscarinic receptor is an autoregulator of acetylcholine.
What is the M2 receptor?
The mass of aerosol generated per unit of time.
What is the output rate?
The tendency of a drug to combine with “specific” receptors.
What is affinity?
The total amount of solvent for 1mL of a 1% solution.
10 mg
This receptor is responsible for vasoconstriction and medications that target these receptors are used for nasal decongestion.
What are alpha-1 receptors?
This is the most severe side effect of anticholinergic bronchodilators.
What is intraocular pressure?