Antimicrobial MOA
Cephalosporins
Protein Synthesis Inhibitors
General Antibiotics Part 1
General Antibiotics Part 2
100
Penicillin, Ampicillin, and Piperacillin block cell wall synthesis by inhibiting cross-linking of this Polymer.
What is Peptidoglycan
100
This generation of Cephalosporins has increased activity against Pseudomonas.
What is 4th generation?
100
This 30S inhibitor is the sole bacteriostatic agent.
What is Tetracycline?
100
This drug works by inhibiting bacterial dihydrofolate reductase.
What is Trimethroprim
100
This anti-fungal agent works by disrupting the formation of microtubules.
What is Griseofulvin?
200
Rifampin works by blocking the synthesis of this type of nucleic acid.
What is mRNA
200
This generation of Cephalosporin is most effective against gram-negative infections resistant to other beta-lactams.
What is 3rd generation cephalosporins?
200
Streptomycin, Amikacin, and Gentamycin belong to this class of which type of antibiotic.
What is Aminoglycosides?
200
This is the only drug that is used as a sole agent in TB prophylaxis.
What is Isoniazid (INH)?
200
This anti-fungal drug works by inhibiting the fungal enzyme squalene epoxidase.
What is Terbinafine?
300
Tetracycline blocks protein synthesis at this ribosomal subunit.
What is 30S
300
Cross-hypersensitivity with penicillins is seen in up to what percentage of users?
What is ten percent?
300
Aminoglycosides cause misreading of this type of RNA.
What is Messenger RNA?
300
This TB drug may change body fluids red or orange.
What is Rifampin?
300
This anti-viral medication can also play a role in the management of Parkinson's disease.
What is Amantadine?
400
Linezolid, Clindamycin, and Chloramphenicol block protein synthesis at which ribosomal subunit.
What is 50S
400
These two generations of Cephalosporins are effective against gram-positive cocci.
What is 1st and 2nd generation?
400
Ototoxicity occurs commonly when Aminoglycosides are combined with this type of diuretic.
What is Loop Diuretics?
400
This is the drug of choice for Pneumocystis Carinii Pneumonia
What is Bactrim (Trimethoprim-Sulfamethoxazole)?
400
The drug of choice for treating river blindness is this.
What is Ivermectin?
500
This drug is a Tuberculosis drug that works by blocking mRNA synthesis.
What is Rifampin.
500
This generation of Cephalosporin has the best ability to penetrate the blood-brain barrier.
What is 3rd generation?
500
Combining Aminoglycosides and Cephalosporins leads most commonly to toxicity of this organ.
What is Kidneys (nephrotoxicity)
500
This category of drug blocks the conversion of Lanosterol into Ergosterol in a fungus cell.
What is the Azoles?
500
The most worrisome side-effect of Interferon therapy is this.
What is bone marrow suppression (Neutropenia)
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