Mood Stabilizers
Used in treatment of bipolar mania, this drug is known for its low therapeutic window, teratogenesis, and thyroid complications.
What is lithium?
(Mnemonic: LiTHIUM Low Thyroid, Heart, Insipidus, Unwanted Movements)
This class of antidepressants is first line for treatment of major depressive disorder and generalized anxiety disorder.
What is: SSRIs (selective serotonin reuptake inhibitors)
The first generation antipsychotics act by blocking this receptor, which increases cAMP.
What is D2
This Syndrome occurs when the doctor or patient fails to titrate up their antidepressant, or when the patient overdoses on their serotinergic drug:
What is serotonin syndrome?
Symptoms: 3A's: Activity, Autonomic instability, Altered mental status
Cynthia recently acquired a new ring by becoming engaged. This gemstone is commonly used in engagement rings, not because "it is forever" but because of the falsely elevated price point by DeBeers' false restriction of supply.
What is a diamond?
This drug used in the treatment of bipolar disorder, requires close monitoring of other protein-bound drugs due to its tendency to kick other drugs off albumin.
What is valproic acid/valproate?
Also, LFTs!
Second line treatment for depression and anxiety includes the SNRIs, which act at this side of the neuronal cleft (Pre- or post- synaptic).
Presynaptic (Serotonin and norepinephrine)
This generation of antipsychotics can treat both the positive and negative symptoms of schizophrenia.
What are the atypicals (2nd gen)
The life-threatening effects of lithium toxicity can be treated by administering this:
What is FLUIDS
Also accepted: HEMODIALYSIS
Assuming there are about 50 players on a football team, the Patriots have how many SuperBowl rings amongst their players?
(50 players x ____Number of SuperBowl wins = answer)
6 superbowl wins, so 50x6 = 300 superbowl rings
Carbamazepine's side effect profile is commonly referred to as "The Three D's, which are...
This drug is effective for treatment of generalized anxiety disorder (but not depression!) and unlike SSRIs and SNRIs, does not interact with alcohol.
What is buspirone?
Extrapyramidal symptoms include all of the following EXCEPT:
Muscle spasmsParkinsonism
Tardive dyskinesiaMetabolic syndrome
Akathisia
What is metabolic syndrome?
Mnemonic: ADAPT
Acute Dystonia
Akathisia
Parkinsonism
Tardive dyskinesia
This drug is used as a sleep aid at low doses, but an antidepressant at high doses. Common side effect: priapism.
What is trazadone?
DAILY DOUBLE:
This locale is home to 75% of earth's volcanoes and 90% of its earthquakes. Also a song by Johnny Cash.What is Ring of Fire
Lamotrigine, a mood stabilizer known for its Black Box warning of SJS/TEN, is most effective for this type of bipolar disorder:
What is Bipolar I (or maintenance of Bipolar I)?
DAILY DOUBLE!
TCAs such as amitriptyline, imipramine, and clomipramine are effective in treating resistant depression, but have this dangerous side effect profile known as the 3C's: Tri-C's:
What is Convulsions, Coma, Cardiotoxicity
This 2nd generation antipsychotic is effective in treatment-resistant schizophrenia, schizoaffective disorder, and suicidality in schizophrenia.
What is clozapine
This NDRI used to treat depression has a more favorable sexual side effect profile than other antidepressants, but is also known to exacerbate overactivity and cause seizures in bullimic patients.
What is bupropion
Also accepted: Wellbutrin
The horror film "The Ring" features a girl in a well and a meta-film stating that "You will die in..." this length of time.
What is: "You will die in Seven Days."
Of the following, the drug that is not approved for use in bipolar depression:
quetiapine, lurasidone, sertraline, olanzapine/fluoxetine, cariprazine
What is sertraline?
Bonus: What happens if you give sertraline to a bipolar patient?
The MOAIs have fallen out of use due to the dietary restriction of this amino acid, which can cause hypertensive crisis and CNS overstimulation.
What is tyramine
PSYCH: EASY ONE!
The 2nd generation antipsychotics all cause this EKG finding:
What is prolonged QT
Mirtazapine is an atypical antidepressant that works on these channels:
What is: alpha-2 (antagonist)
5HT2 and 5HT3 (antagonist)
H1 (antagonist)
(Must get alpha-2, serotonin, and H1 for credit!)
FINAL JEOPARDY: PLACE YOUR BETS
Sauron, the primary antagonist of The Lord of the Rings, created 3 rings for the elves, 7 rings for the dwarves, 9 rings for men, and 1 ring to rule them all. He makes his home in this fictional place, where our heroes must journey to destroy the one ring.What is MORDOR
Also accepted: MOUNT DOOM