Classification
first classification of drug
sympathomimetics
what are the actions of sympathomimetics
Stimulate the sympathetic nervous system
They produce symptoms of fight-or-flight response
They may be natural or synthetic agents
They may be catecholamines or noncatecholamines
name the two receptors.
alpha and beta receptors.
what is another name for adrenaline?
Epinephrine
what is the action of sympatholytics?
inhibits the sympathetic nervous system.
Produce action opposite to those of sympathomimetics.
second classification of drug
sympatholytics
what is another name given to this type of drug
These drugs are also called adrenergic agonists
where are alpha 1 receptors located
predominantly located at
postsynaptic sites on smooth muscles and glands.
one which receptor does adrenaline have more effect?
Has more effect on beta than on alpha receptors
what are the action of these agents specific to?
The actions of these agents are specific to
either alpha or beta blockade
third classification of drug
parasympathomimetics
what do sympathomimetics do to blood vessels and muscus membrane
Vasoconstriction of blood vessels of the skin and
mucous membrane.
what actions of sympathomimetics are alpha 1 receptors involved in?
vasoconstrictor actions
List 3 uses of adrenaline
Used for emergency management of anaphylaxis
Used in advanced cardiac support
Used for its vasoconstrictor properties in local
anaesthetic for dental use
Another name for sympatholytics.
adrenergic blockers
andrenergic antagonist
fourth classification of drug
parasympatholytics
what happens to the bronchi through the action of a sympathomimetic?
Dilation of the bronchi
where are alpha 2 receptors located?
presynaptic nerve terminals
Name three uses of sympathomimetics.
1.They are used where haemodynamic support
is required as in heart failure or arrest.
2. They are used in shock, including
anaphylactic shock.
3. Myocardial infarction
4. Bradycardia
5. Hypotension (often associated with
anaesthesia)
6. Their bronchodilating activity makes them
useful in respiratory disorders and beta 2
agonists have a major role in the management
of diseases like asthma and COPD.
what does beta 1 receptor do?
what does beta 2 receptors do?
1. Mediate the effects of sympathomimetics
on the heart.
2. Mediate bronchodilation and uterine
relaxation