Suboxone sublingual film is indicated to treat _____.
What is opioid dependence?
100
Up to __________ is recommended induction dosage of Suboxone sublingual film on Day 1.
What is 8 mg / 2 mg?
100
This is the percent weighting for waivered and prospect calls.
What is 50%-50%?
100
At this dose there have been reported deaths of opioid naïve individuals.
What is a 2 mg dose of buprenorphine?
100
Buprenorphine is a _____ ________ at the mu-opioid receptor.
What is a partial agonist?
200
__________ is the law that limits the prescription use of Suboxone sublingual film in the treatment of opioid dependence to physicians who have met certain qualifying requirements?
What is the Drug Addiction Treatment Act?
200
This dose or higher has not demonstrated a clinical advantage.
What is 24 mg / 6 mg?
200
This is the pregnancy category for Suboxone sublingual film.
What is Pregnancy Category C?
200
This drug may be of value for the management of buprenorphine overdose.
What is naloxone?
200
Comparisons of buprenorphine to full opioid agonists suggests that sublingual buprenorphine produces typical opioid agonist effects which are limited by a ______ _______ .
What are the four dosage strengths of Suboxone sublingual film?
300
________ is the recommended dose on Day 2 of induction.
What is the single daily dose of up to 16 mg /4 mg?
300
This is Marty's stretch goal for the number of new certified physicians in 2015.
What is 4,000?
300
__________has been reported in infants of women treated with buprenorphine during pregnancy.
What is neonatal withdrawal?
300
Based on all studies performed with Suboxone sublingual film, buprenorphine has a mean elimination half-life from plasma ranging from _____ to _____ hours.
What is 24 to 42 hours?
400
__________ is the recommended dose range during maintenance as a single daily dose.
What is 4 mg/1 mg to 24 mg/6 mg buprenorphine/naloxone?
400
These patients may be inducted with either Suboxone sublingual film or with sublingual buprenorphine monotherapy.
What do you use for induction with patients dependent on heroin or short acting opioids?
400
This is the growth rate target for Indivior that was set by Shaun Thaxter, CEO.
What is 15% growth year-over-year?
400
This can happen when unintentional pediatric exposure to Buprenorphine occurs.
What is severe, possibly fatal, respiratory depression with accidental exposure?
400
Naloxone has a mean elimination half-life from plasma ranging from _____ to _____ hours.
What is 2 to 12 hours?
500
These patients that may have reduced clearance of naloxone to a much greater extent than buprenorphine, and should avoid treatment with fixed combination products.
Who are severe hepatically impaired patients?
500
This dosage should be used with patients that are switching between buprenorphine and naloxone or buprenorphine only sublingual tablet and Suboxone sublingual film.
What is the corresponding dosage of the previously administered product?
500
Safety and effectiveness of Suboxone sublingual film has not been established in patients below this age.
What is age 16?
500
This can happen when buprenorphine, particularly by IV route, is taken in combination with benzodiazepines or other CNS depressants (including alcohol).
What is significant respiratory depression and death?