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Clinical manifestations of Respiratory Distress Syndrome include..
What is tachypnea (>60 breaths/min), dyspnea, pronounced intercostal or substernal retractions, fine inspiratory crackles, audible expiratory grunt, flaring of the external nares, cyanosis or pallor, apnea and with progression of the condition, deteriorating vital signs (bp, apnea, body temp instability)