Practica Dr dilemma unimetro 2025 #2

Reumatology

100

• IL-6 inhibitor approved for scleroderma-associated interstitial lung disease

Tocilizumab

200

• The target serum uric acid level for most patients with gout undergoing urate-lowering therapy is

Less than  6 mg/dl

300

• The ultrasound sign that reflects the deposition of monosodium urate crystals on the surface of the articular hyaline cartilage is called

Double contour sign

400

• Moderate lupus activity is defined according to the SLEDAI score as

7-12 points

500

• The inflammasome activated by monosodium urate crystals and plays a crucial role in gout attacks is

NLRP3

Neurology

100

• What is the first-line treatment for status epilepticus in adults?

IV benzodiazepines (e.g, Lorazepam)

200

• Which type of brain hemorrhage is typically associated with a thunderclap headache?

Subarachnoid hemorrhage

300

• What is the most common artery affected in large-vessel ischemic stroke?

Middle cerebral artery

400

• This type of test is used to detect subclinical demyelinating lesions in multiple sclerosis

Evoked potentials

500

• What is the most common genetic risk factor for late-onset alzheimer’s disease?

APOE 4 allele

Nephrology

100

• The urea excretion fraction index (FEurea) that suggests a prerenal etiology is

FEurea <35%

200

• The minimum glomerular filtration rate (GFR) recommended for treating a patient with chronic kidney disease and diabetes mellitus with SGLT12 inhibitors is

>20 mL/min/1.73 m2

300

• The currently recommended formula to estimate GFR without considering race is

CKD-EPI 2021

400

• The glomerulopathy with the highest risk of renal vein thrombosis in nephrotic syndrome is

Membranous nephropathy

500

• The gene most commonly associated with focal segmental glomerulosclerosis (FSGS) is

apol 1/NPHS2

Gastroenterology

100

• This is the purpose of the MELD lactate score (MELD-LA)

To predict in hospital mortality

200

• This serological marker indicates active viral replication and high infectivity in the context of HBV infection

HBeAg antigen detection

300

• The medications that have been shown to improve histology in patients with NASH in a multicenter randomimzed controlled trial

Vitamin E

400

• This scoring system is used in the U.S to prioritize the sickest patients for liver transplantation

MELD-Na

500

• The first line therapy is recommended for patients with BCLC stage C HCC and preserved liver function

Atezolizumab plus bevacizumab

Dermatology

100

• Which skin infection is characterized by the presence of honey-colored crusts?

Impetigus

200

• What is the first line treatment for mild cases of impetigo?

Topical antibiotics (Mupirocin)

300

• In recurrent cellulitis, which underlying condition is most commonly associated?

Lymphedema

400

• Which clinical feature differentiates cellulitis from necrotizing fasciitis?

Rapid progression and severe pain in necrotizing fasciitis

500

• This IL-23 inhibitor is approved for psoriatic arthritis

Guselkumab or Risankizumab