Delivery
Per CDC recommendation, preoperative skin cleansing before cesarean delivery should be performed with this type of solution unless contraindicated.
What is an alcohol-based solution (chlorhexidine–alcohol)?
For obstetric patients known to be MRSA colonized undergoing cesarean delivery, consideration may be given to adding a single dose of this antibiotic to the standard prophylaxis regimen.
What is vancomycin?
This is the preferred timing for antibiotic prophylaxis in regard to cesarean delivery.
What is within sixty minutes of incision time or ASAP once the incision is made?
For preterm labor with intact membranes, this type of prophylaxis should be administered if lab results are not available.
What is GBS prophylaxis?
Patients with OASIS tears have been shown to have lower rates of perineal wound complications with this class of antibiotic
What is a second-generation cephalosporin (cefotetan or cefoxitin)?
This is the first-line single-dose antibiotic class of choice for cesarean delivery prophylaxis, absent significant drug allergy.
What is a first-generation cephalosporin (cefazolin)?
High-risk patients with infective endocarditis should receive this prophylaxis.
What is amoxicillin 2 g PO or 2g IV.
For this weight class of patients, 1g of Cefazolin is appropriate.
What is 80kg or less?
This is the recommended course for PPROM less than 34 0/7 weeks.
What is two days of IV ampicillin/Erythymycin and five days of amoxicillin and erythromycin
What is no type? Evidence is insufficient to recommend antibiotic prophylaxis for this history; ultrasound or exam-indicated cerclages.
This low-alcohol concentration of chlorhexidine gluconate is considered safe and effective for off-label use as a vaginal surgical preparation.
What is 4%?
For patients allergic to penicillin or ampicillin who need IV endocarditis prophylaxis, this is the antibiotic regimen is used.
What is Clindamycin 600 mg IV?
After this time period and/or event, patients should receive an additional intraoperative dose of the same antibiotic given for pre-incision prophylaxis. (2)
what is four hours or what is blood loss greater than 1500mL?
This antibiotic combination is not recommended for preterm PROM, given an increased risk of neonatal necrotizing enterocolitis demonstrated in a UK multicenter trial.
What is amoxicillin–clavulanic acid?
This complication of cesarean delivery carries an increased risk of postpartum endometritis even in the presence of antibiotic prophylaxis.
What is manual removal of the placenta?
A single randomized trial found that this concentration (%) of chlorhexidine vaginal wipes before elective cesarean reduced overall infectious morbidity, largely by reducing endometritis.
What is 0.25%?
This is the feasible time interval to give endocarditis prophylaxis for those not already receiving intrapartum antibiotic therapy for another indication that would also provide coverage against endocarditis.
What is 30–60 minutes before anticipated time of delivery?
Antibiotic prophylaxis administered up to 60 minutes before skin incision decreases the incidence of these two outcomes.
What is postpartum endometritis and total infection morbidity?
This macrolide has been substituted for erythromycin in preterm PROM regimens during periods of erythromycin shortage?
What is azithromycin?
Antimicrobial prophylaxis is recommended for uterine evacuation performed for either of these two indications.
What is induced abortion or early pregnancy loss?
This is the full weight-based dosing of the alternative combination regimen for patients with a significant penicillin or cephalosporin allergy.
What is clindamycin 900 mg plus an aminoglycoside 5 mg/kg?
These groups are the highest-risk cardiac population for whom endocarditis prophylaxis at vaginal delivery is considered reasonable. (4)
What is unrepaired cyanotic congenital heart disease, patient with previous infective endocarditis, patients with prosthetic cardiac valves or cardiac transplant recipients with valve regurgitation due to a structurally abnormal valve.
This time period is the half-life of cefazolin.
What is two hours?
Following preterm labor with intact membranes, infants prenatally exposed to erythromycin had significantly higher rates of what when compared to unexposed infants.
What is functional impairment?
What is pre-existing, subclinical chorioamnionitis?