ADME
This term describes how a drug moves from the site of administration into the blood stream
What is absorption?
This refers to the desired effect a medication is intended to produce
What is therapeutic effect?
This route has no barriers and delivers medication directly into the bloodstream
What is intravenous?
This "Right" ensure the medication is given to the correct individual
What is "Right patient?"
These mild ADRs include nausea, headache, or drowsiness
What are side effects?
This pharmacokinetic phase primarily occurs in the liver and changes drugs into inactive forms
What is metabolism?
This term refers to the time it takes for 50% of a drug to be eliminated from the body
What is half-life?
This oral route allows rapid absorption through mucous membranes?
What is sublingual/buccal?
These medications require extra caution and often use Tall-Man lettering
What are high-alert medications?
This ADR is an immune response and can be life-threatening
What is an allergic reaction?
Protein binding primarily affects this pharmacokinetic phase
What is distribution?
These drugs bind to receptors and block normal receptor activity
What are antagonists?
Absorption of medications given IM or SQ depend on this factor at the injection site
What is blood perfusion?
These substances are classified into Schedules I-V due to abuse potential
What are controlled substances?
This type of ADR produces the opposite effect of what is expected
What are paradoxical effects?
This effect occurs when oral medications are metabolized before reaching systemic circulation
First-pass effect
This index represents the range between effective and toxic drug levels?
What is therapeutic index?
This route has very slow absorption and is usually intended for local effects
What is topical?
Name three of the five rights
Dose, time, route, patient, medication
This population has increased risk due to polypharmacy and decreased renal function
Who are older adults?
Increased renal blood flow during this pregnancy stage accelerates drug excretion
These drugs act as both agonists and antagonists at different receptor sites
What are partial agonists?
Give an example of a schedule 2 drug
Opioids/narcotics (fentanyl, hydromorphone, vicodin, etc)
Stimulants (Adderall)
Reporting serious ADRs in the US is done through this system
What is MedWatch?
This list identifies potentially inappropriate medications for older adults
What is Beers Criteria?