Drug Regulation
What drug schedule is described as a high potential for abuse, but has legitimate medical purposes?
Schedule II
What types of medication names are the following:
4-chloro-N-furfuryl-5-sulfamoxylanthranilic
furosemide
Lasix
Chemical
Generic
Brand
The ability of a medication to bind with a particular receptor site.
Affinity
Any abnormal or harmful effects caused by exposure to a chemical. Can include functional or anatomical damage, irreversible change in homeostasis, or increased a patient's susceptibility to any other chemical or biologic stress.
Adverse or Untoward Effects
Two of the fastest routes of medication
IV/IO
Medications such as Atropine, Aspirin, Digoxin, and Morphine are derived from ______.
Plants
What component of medication profile is described as any condition or disease that is known to render some particular line of treatment improper or undesirable?
Contraindication
These types of medications prevent endogenous and exogenous agonist chemicals from reaching cell receptor sites and initiating or altering a particular cellular activity.
Antagonist Medications
The relationship between the median effective dose and the median lethal dose or median toxic dose is known as the _________ _____.
Therapeutic Index
Name 3 contraindications of an IO
Fracture
Prosthetic Limb (duh)
Osteoporosis
Osteogenesis Imperfecta
Bilateral Knee Replacements
This form of medication is described as small particles of medication designed to be dissolved or mixed into a solution or liquid.
(Ex. Glucagon, Methylprednisolone)Powder
What patient populations have a slower medication absorption and elimination rate?
Pediatrics and Geriatrics
The ability to initiate or alter cell activity in a therapeutic or desired manner
Efficacy
This type of medication interaction is described as two medications with a similar effect combine to produce an effect greater than the sum of the medications' effects.
The ability of medication to pass through the GI tract into the bloodstream
GI motility
What drug schedule is described as having a high potential of abuse without any legitimate medical purpose?
Schedule I
What ways of improper medication storage can make medications ineffective or unsafe for use?
Extreme heat/cold, direct sunlight, physical damage to medication containers
Name 3 factors that affect response to medications
This process is used to enhance the distribution of certain medications, electrolytes, and IV fluids.
Osmosis
It is recommended for this route of medication to administer 2 - 2.5 times the IV dose followed by a 5 - 10mL flush
Endotracheal
What is the federal agency responsible for approving new medications from the market?
US Food and Drug Administration (FDA)
EMS agencies and paramedics jointly responsible for adhering to federal, state, and local regulations regarding security and accountability of __________ __________.
Controlled Substances
What are the formulas to calculate ideal body weight (kg) in men and women?
Men: 50 + (2.3 x patient's height in inches over 5ft)
Women: 50 + (2.3 x patient's height in inches over 5ft)
The time needed in the average person for the metabolism or elimination of 50% of the substance in the plasma
Half-Life
Thee percentage of unchanged medication that reaches the systemic system
Bioavailability