All about clozapine
Hormones
Depression specifiers
Trinucleotide repeat expansions
Paraphilic disorders
100
This is the minimum ANC required to start clozapine in the general population

1500/µL

100

Lithium may cause one to lose sensitivity to this hormone.

What is ADH?

100

Increased or excessive involvement in activities that have a high potential for painful consequences

What is with mixed features?

100

Chorea, akinesia, cognitive decline, behavioral changes

What is Huntington disease? (CAG)

100

Observing another person naked, disrobing, or engaging in sexual activity

What is voyeuristic disorder?

200

This side effect of clozapine is best treated topically, rather than using systemic medications.

What is sialorrhea?

200

This hormone's fluctuation is most associated with premenstrual dysphoric disorder (PMDD) 

What is progesterone? (particularly its withdrawal)

200

Feeling that the individual might lose control of himself or herself

What is with anxious distress?

200

Large protuding chin, large testes, hypermobile joints, mitral valve prolapse

What is Fragile X syndrome? (CGG)

200

Sexual arousal from the physical or psychological suffering of others

What is sexual sadism disorder?

300

Target minimum clozapine blood level

What is 350 ng/mL?

300

The hunger hormone

What is ghrelin?

300

Depression that is regularly worse in the morning

What is with melancholic features?

300

Cataracts, premature hair loss in men, myotonia, arrhythmia, gonadal atrophy (men), ovarian insufficiency (women)

What is myotonic dystrophy? (CTG)

300

Touching or rubbing against a nonconsenting person

What is frotteuristic disorder?

400

This medication can increase the ANC in patients on clozapine through its action on GCSF.

What is lithium?

400

The satiety signal

What is leptin?

400

A long-standing pattern of interpersonal rejection sensitivity (not limited to episodes of mood disturbance) that results in significant social or occupational impairment

What is with atypical features?

400

Ataxic gait, dysarthria, kyphoscoliosis, hypertrophic cardiomyopathy

What is Friedrich ataxia? (GAA)

400

This is the paraphilic disorder that includes specifying "body part(s)" or "nonliving object(s)"

What is fetishistic disorder?

500

This enzyme can be elevated early in clozapine treatment, but you needn't always worry about infection

What is CRP

500

Zuranolone's inspiration

What is allopregnanolone?

500

Catalepsy

What is with catatonia?

500

Progressive gait ataxia, progressive limb ataxia, nystagmus, dyssynergia, dysmetria, dysdiadochokinesia, dysarthria

What is spinocerebellar ataxia?

500

A specifier for sexual masochism disorder in which arousal is related to restriction of breathing

What is "with asphyxiophilia"?

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