This man is known as the father of "scientific psychiatry," with his work forming the basis of the modern psychiatric classification system.
He emphasized diagnosis based on observable symptoms.
He was the first to distinguish dementia praecox and manic depressive psychosis
Emil Kraepelin (1856-1926)
This medication for alcohol dependence blocks the enzyme aldehyde dehydrogenase.
Disulfuram
Which of the following conditions was formerly called psychogenic amnesia?
A. Depersonalization disorder
B. Dissociative amnesia
C. Dissociative fugue
D. Dissociative Identity disorder
E. Dissociative disorder not otherwise specified
B. Dissociative amnesia
"Inability to recall important personal info, usually of a traumatic nature, that is too extensive to be explained by normal forgetfulness."
This was a randomized, double-blind study designed to compare the effectiveness of atypical and conventional antipsychotic drugs.
Conclusion: Patients receiving olanzapine experienced a longer time to discontinuation, compared with other antipsychotics, but they also had greater weight gain, hyperglycemia, and hyperlipidemia.
CATIE (2005)
Which of the following neurotransmitters is not stored in synaptic vesicles, but synthesized de novo?
A. GABA
B. Histamine
C. Glutamate
D. Acetylcholine
E. Endocannabanoids
E. Endocannabanoids
The "father of psychoanalysis," championed the idea that much of mental life exists at a level that is outside of our awareness, and that these unconscious forces yield great influence on human conduct. His ideas permeated American psychiatry throughout most of the 20th century, and this man is responsible for opening up psychiatry to outpatient practice.
Sigmund Freud (1856-1939)
This psychotherapy for addiction utilizes a disease-model approach and emphasizes concepts, such as acceptance of the disease and surrender to help beyond oneself.
12-step facilitation (or a 12-step program)
Which of the following tests is MOST often used to record the severity and lifetime presence of specific symptoms of OCD?
A. BDI
B. BPRS
C. HANDS
D. Y-BOCS
E. Y-MRS
This study was funded by the National Institute of Mental Health to determine the effectiveness of different treatments for people with major depressive disorder (MDD) who have not responded to initial treatment with an antidepressant. With its publication, this study became the largest and longest study of its time to evaluate depression treatment.
Conclusion: When more treatment steps are required, lower acute remission rates and higher relapse rates during the follow-up phase are to be expected. Augmentation of citalopram with bupropion may be particularly advantageous in people who require additional treatment.
STAR-D (2006)
Depression is considered to be independent of alcohol use if clearly occurring prior to the onset of abuse or continuing once abstinence is reliably achieved for:
A. one week
B. two weeks
C. one month
D. 3 months
E. 6 months
C. one month
An early follower of Freud, this Swiss psychiatrist is perhaps best known in psychiatry as the originator of the term "schizophrenia."
Eugen Bleuler (1857-1939)
A 21 year old patient is dropped off at an ED. He is agitated, but not aggressive towards staff, and states that computers in the ED are flashing messages at him. He says, "I need my knife to protect myself." This substance is found on urine toxicology as the etiology for his psychosis.
amphetamine
Which of the following is highly protein-bound?
A. Diazepam
B. Gabapentin
C. Lithium
D. Memantine
E. Venlafaxine
A. Diazepam
Most psych drugs are >80% protein bound. It is considered highly protein bound if >90% protein bound in plasma
Fluoxetine, Aripiprazole and diazepam are all highly protein bound examples of psych drugs
This study was a double-blind, randomized, placebo-controlled study designed to evaluate the effectiveness of treatments for bipolar disorder and to provide results that would be generalizable to routine clinical practice.
Conclusion: Adjunctive treatment with antidepressants does not appear to improve clinical outcomes in people with bipolar disorder taking a mood stabilizer.
STEP-BD (2007)
Clanging is an abnormal finding recorded under which of the following elements of the MSE?
A. Speech
B. Cognition
C. Perception
D. Thought content
E. Thought process
E. Thought process
CBT was first developed in the 1960s by this psychiatrist who formulated the idea for the therapy after noticing that many of his patients had internal dialogues that were almost a form of them talking to themselves.
Aaron T. Beck (1921- Nov 1 2021)
This symptom is considered to be the hallmark of amphetamine-induced psychosis.
Paranoia
Which of the following is the MOST common neurologic complication of HIV infection?
A. Cerebellar dysfunction
B. Distal sensory polyneuropathy (DSP)
C. Ischemic Cerebrovascular disease
D. Spinal stenosis
E. Syncope
B. Distal sensory polyneuropathy (DSP)
In this study, researchers conducted a randomized, open-label, trial to evaluate whether a combination of lithium plus valproate sodium is better than monotherapy with either drug alone for relapse prevention in bipolar I disorder.
Conclusion: Combination therapy with lithium, plus valproate, is more likely to prevent relapse than is valproate monotherapy, regardless of the baseline severity of illness.
BALANCE (2010)
According to WHO, which of the following is the most common global barrier to accessing mental health treatment?
A. Language
B. Financial cost
C. Low Perceived Need
D. Lack of transportation
E. Availability of providers
C. Low Perceived Need
When it comes to modern psychiatric treatment, none have had a greater influence on the field than this man. Often regarded as the "father of psychopharmacology," His work in the 1950s led to the development of the very first antipsychotic and antidepressant medications.
Nathan S. Kline (1916-1983)
This is the 8th step in the 12 Steps program
Which of the following conditions is MOST closely associated with the orbital or medial frontal cortex, the caudate nucleus and the globes pallidus?
A. Depression
B. Mania
C. OCD
D. Paraphilias
E. Psychosis
C. OCD
THE NIHM funded this study to compare the acute efficacy and durability of several treatment approaches in youth with separation, generalized, and social anxiety disorders.
Conclusion: Among youth with anxiety disorders, using a combination treatment approach of cognitive behavioral therapy, plus sertraline is superior to either component alone.
CAMS (2014)
To limit the risk of QT prolongation, citalopram should NOT be co-administered with meds that inhibit which of the following P450 enzymes?
A. 1A2
B. 2C19
C. 2C9
D. 2E1
E. 2B6
B. 2C19