Mood
In what gender is Bipolar II disorder more common?
Women
The efficacy of buspirone in the treatment of anxiety disorders is limited to which disorder?
Generalized anxiety disorde
What is the lifetime prevalence of panic disorder in the U.S. general population?
3.8%. (accept 4% +/- 0.5%)
Behavioral treatment for obsessive-compulsive disorder (OCD) typically includes what?
Exposure and response prevention
Recall of a personal experience identified with the self, such as attending a basketball game, involves which type of memory?
Episodic memory.
Unlike sertraline, paroxetine has a relatively high affinity for which monoamine receptor?
Norepinephrine transporter (NET)
What would be the most likely diagnosis for a child presenting with persistent, chronic irritability and frequent episodes of extreme behavioral dyscontrol?
Disruptive mood dysregulation disorder (DMDD).
What is the most common side effect of aripiprazole in adults?
Akathisia
According to twin studies, what is the estimated heritability of panic disorder?
40% (accept +/- 5%)
Shortly after becoming ill with a respiratory infection, a 10-year-old boy begins to display symptoms of checking. What organism is most likely to be responsible for his infection and psychiatric symptoms?
Group A beta-hemolytic streptococcus (Streptococcus pyogenes). In PANS, children affected by streptococcus may exhibit obsessive compulsive and related symptoms that sometimes (but not always) resolve after effective treatment of the streptococcal infection. Studies have found that the basal ganglia must be affected by the infection in order for PANS to occur.
What pattern characterizes the nature of memory loss in dissociative amnesia?
The memory loss is generally for traumatic or stressful events.
Unlike paroxetine, sertraline has a relatively high affinity for which monoamine receptor?
Dopamine transporter (DAT)
A 6-year-old girl with a chronic negative mood and frequent and severe verbal and behavioral outbursts in response to common stressors is most likely to go on to develop which disorder in adulthood?
Major depressive disorder
What is the best-established pharmacotherapy for treatment of specific phobia?
Benzodiazepines
What is the minimum duration of symptom persistence required for a diagnosis of generalized anxiety disorder (GAD)?
Six months.
What is the approximate lifetime prevalence of obsessive-compulsive disorder (OCD) in the U.S. general population?
2.5% (accept 2-3%)
Experiencing of others as unreal, dreamlike, or foggy is an example of what?
Derealization
A possible explanation for the postulated modest superiority of S-citalopram over citalopram on some measures of antidepressant activity is . . .
The R-enantiomer of citalopram may interfere with the activity of the S-enantiomer
What symptoms are less commonly associated with bereavement and can indicate a major depressive episode even in light of a significant loss?
(1) feelings of worthlessness,
(2) suicidal ideation (distinct from wanting to join a deceased loved one),
(3) psychomotor retardation, and
(4) severe impairment in overall functioning
What is the only class of medication shown to be effective in reducing the full range of posttraumatic stress disorder (PTSD) symptoms?
SSRIs
Which of the anxiety disorders has the oldest median age at onset?
Among the anxiety disorders, generalized anxiety disorder has the oldest median age at onset, 30 years.
Among individuals with obsessive-compulsive disorder (OCD), what is the most common comorbid psychiatric diagnosis?
Major depressive disorder
Which of the dissociative disorders is considered to be the most common?
Dissociative amnesia
You start your patient, a 72-year-old man, on trazodone, advising him to take the medication at bedtime. He calls you the next day to tell you that he was light-headed and dizzy and almost fell when he got out of bed that morning. Knowing the pharmacological profile of trazodone, you attribute this side effect to which of the following properties of the drug?
Potent antagonist of postsynaptic α1-adrenergic receptors
What diagnoses cannot co-exist with DMDD, according to Criterion J?
oppositional defiant disorder, IED, or bipolar disorder
Which widely used medication class may interfere with extinction learning and increase the risk of posttraumatic stress disorder (PTSD) after a traumatic event?
Benzodiazepines
Which of the anxiety disorders has the youngest median age at onset?
Among the anxiety disorders, social anxiety disorder (social phobia) has the youngest median age at onset, at 15 years.
What is the concordance rate of obsessive-compulsive disorder (OCD) in monozygotic twins?
A review of twin studies found that there is a strong heritable component to OCD, with concordance rates of 80–87% in monozygotic twins compared with 47%–50% in dizygotic twins (van Grootheest et al. 2005).
What condition is characterized by persistent feelings of unreality, detachment, or estrangement from oneself?
Depersonalization/derealization disorder
A relatively rare (1 in 6,000) but dramatic side effect associated with trazodone is . . .
Priapism