Antidepressants
Antipsychotics
What's Going On?
It's not you, it's me
Potpourri
100

This atypical antidepressant should not be used in those with an eating disorder, seizure disorder, or alcohol use disorder. 

Bupropion

100

This first generation antipsychotic is the most common first generation used, and can be given in PO, IM, and IV formulations

Haloperidol

100

A 15 year old girl is walking to City Market when she suddenly experiences chest tightness, shortness of breath, dizziness, and an intense fear of dying. She is brought to the ED where physical workup is unremarkable. What is the most likely diagnosis?

Panic disorder

100

This personality disorder is characterized by a need for excessive admiration, an inflated sense of importance, a lack of empathy, and by being interpersonally exploitative

Narcissistic personality disorder

100

This medication class is considered first line treatment for alcohol withdrawal

Benzodiazepines

200

All patients taking a monoamine oxidase inhibitor need to be counseled about to not eat foods rich in this substance

Tyramine

200

Metabolic side effects are unfortunately common when using an antipsychotic. Name one of the two worst medication offenders when it comes to these side effects.

Olanzapine or Clozapine

200

A 28 year old nonbinary person presents to your ED disorganized, paranoid, delusional, and responding to internal stimuli. Collateral confirms this has been occurring for two months. What is the most likely diagnosis?

Schizophreniform disorder

200

This common personality disorder has the highest rate of suicide among personality disorders.

Borderline personality disorder (8-10% eventually commit suicide)

200

This medication is a partial mu opioid receptor agonist, useful in the treatment of opioid use disorder

Buprenorphine

300

The SSRI class of antidepressants is typically first line for the treatment of depression for this reason

Safety (low adverse effects)

300

This lab is required weekly when starting the medication clozapine for schizophrenia (and why?).

CBCD, for agranulocytosis (low neutrophil count, risk of life threatening infection).

300

A 30 year old man presents to your primary care clinic with three weeks of sadness, difficulty sleeping, poor concentration, 5 lb weight loss, a lack of interest in playing with his children, and difficulty functioning at work. This is following the loss of his father one month ago. What's the diagnosis?

Major depressive disorder

300

This is the only personality disorder which, when diagnosed in an adult, requires evidence of disordered behavior prior to age 15

Antisocial personality disorder

300

This is the dopaminergic pathway responsible for the negative symptoms of schizophrenia

Mesocortical pathway

400

Tricyclic antidepressants are dangerous to overdose on, with severe outcomes commonly remembered by the nemonic, the "three Cs."

Cardiac (arrhythmias). Convulsions. Coma.

400

Akathisia is a movement disorder characterized by a feeling of inner restlessness and an inability to sit still. It is commonly caused by antipsychotics like aripiprazole. This common medication is used to treat akathisia.

Beta-blockers like propranolol

(Also accept reducing dose, benzodiazepines and anticholinergics like benztropine)

400

A 52 year old man presents to the ED saying, "I'm dead, doc. I have no lungs, no liver, no kidney. My heart is barely beating. I am waiting to die." He endorses fatigue. He denies all other symptoms. 

Delusional disorder, somatic subtype (Cotard's delusion).

400

A 35-year-old female has recently quit her job in order to start a small business. She claims that the spirits have told her to sell trinkets each of which has a unique power. She is known for dressing oddly and due to her strange behavior has trouble making friends.

Schizotypal Personality Disorder

400

This sleep disorder often improves with the addition of iron pharmacotherapy

Restless leg syndrome

500

This antidepressant has dual indications for fibromyalgia and diabetic peripheral neuropathic pain, among others

Duloxetine

500

Name three medications approved for bipolar depression.

1. Quetiapine, 2. Lurasidone, 3. Olanzapine + fluoxetine (Symbyax), 4. Cariprazine, 5. Lumateperone. 

500

This is the diagnosis made for patients who have severe, recurrent outbursts that occur on average 3+ times a week. Notably, these patients' moods are typically irritable between outbursts.

Disruptive Mood Dysregulation Disorder

500

This is the most common personality disorder

Obsessive-Compulsive Personality Disorder (7.9%)

500

This sleep disorder has a strong relationship to neurodegenerative disorders

Rapid Eye Movement (REM) Sleep Behavior Disorder

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