Pharmacokinetics
Lipid-soluble molecules can easily pass through this protective barrier that helps regulate what enters the brain from the bloodstream.
What is the blood brain barrier?
What is this called when a drug activates a receptor by binding directly to it AND producing the same effect as the natural neurotransmitter?
This neurotransmitter will have you feeling good, but watch out you could get addicted.
What is dopamine?
Dry mouth, constipation, confusion, and blurred vision occur when drugs block this receptor.
What is M1 receptor?
This term refers to the need to increase dosage to maintain a drugs effect.
What is tolerance?
This route of administration includes oral, sublingual, and rectal.
What is enteral route?
When psychoactive drugs alter neurotransmitter release, block reuptake, or prevent breakdown in the synapse, they are interfering with this fundamental mechanism of neural communication.
What is synaptic transmission?
Endorphins are associated with this feeling. Also the name of the popular HBO show starring Zendaya.
What is euphoria?
What is the D2 receptor?
Alcohol has a lower therapeutic index than any of these substances (name 2).
What is cocaine, ecstasy, codeine, mescaline, roofies, Special K, Nitrous Oxide, Mushrooms, LSD, Cannabis?
Known by the acronym ADME, these four pharmacokinetic processes describe a drug’s path through the body.
What is Absorption, Distribution, Metabolization, and Elimination
The antipsychotic haloperidol can bind so tightly to dopamine D2 receptors that it displaces dopamine from the receptor and occupies its place, demonstrating its strength in receptor binding.
What is Affinity?
Associated with fight or flight, this neurotransmitter is produced in stressful situations and leads to increased heart rate and blood flow.
A patient gains significant weight after starting this drug due to the blockage of this serotonin receptor involved in appetite regulation.
What is 5-HT2C
A drug produces sedation, depressed neuronal activity, and memory loss due to reduced excitatory glutamate signaling and increased inhibitory signaling
What are GABA or NMDA systems?
This term describes the proportion of a drug that reaches the bloodstream and is able to produce an active effect.
What is Bioavailability?
Order from the most efficacious and potent. Look at the board to answer.
What is B, C, A, D?
Low levels of this neurotransmitter might be the cause of anxiety.
What is GABA?
What is the H1 receptor?
These substances were labeled under the CNS stimulant drug class. (name 3)
Methamphetamine, cocaine, caffeine, nicotine.
The definition of half-life.
What is a period of time required for the concentration or amount of drug in the body to be reduced by one-half?
A medication reduces brain signaling so strongly that increasing neurotransmitter levels cannot restore the full effect because some receptors are no longer functioning properly. This would make it harder to override!
What is a non-competitive antagonist effect?
These are some of the things associated with cannabinoids. (give at least 3)
Learning, memory, neurodegeneration, addiction, epilepsy, appetite, and stroke.
A psychiatric medication acts on three major receptor systems: dopamine receptors involved in psychotic symptoms, as well as blocking a serotonin receptor that helps reduce extrapyramidal side effects. Another serotonin receptor affected by these medications has been linked with improved cognition and potential antidepressant effects.
What are D2, 5HT2A, AND 5HT2C?
What are opioids?