Misc
The thyroid gland is responsible for producing thyroid hormone in humans. Pre-mRNA of thyroid hormone gene is only present in thyroid gland cells. Which of the following is true?
A. The thyroid hormone gene does not show DNA looping in the cells of other tissues.
B. The thyroid hormone gene is under temporal regulation of gene expression in the cells of other tissues.
C. The thyroid hormone gene is under spatial regulation of gene expression in the cells of other tissues.
D. Both A and C
E. All of the above
The thyroid gland is responsible for producing thyroid hormone in humans. Pre-mRNA of thyroid hormone gene is only present in thyroid gland cells. Which of the following is true?
A. The thyroid hormone gene does not show DNA looping in the cells of other tissues.
B. The thyroid hormone gene is under temporal regulation of gene expression in the cells of other tissues.
C. The thyroid hormone gene is under spatial regulation of gene expression in the cells of other tissues.
D. Both A and C
E. All of the above
TATA box binding (TBP) protein binds directly to:
A. Spacer DNA
B. Cis-regulatory sequences
C. Intron consensus sequences
D. Promoter region
E. None of the above
TATA box binding (TBP) protein binds directly to:
A. Spacer DNA
B. Cis-regulatory sequences
C. Intron consensus sequences
D. Promoter region
E. None of the above
Which of the following is NOT true for transcriptional regulation of eukaryotic genes?
A. There is one promoter region, but multiple cis-regulatory regions for a particular gene.
B. Multiple cis-regulatory regions of a gene either all equally activate transcription or all equally repress transcription.
C. The lariat structure generated during splicing is a component of complexes at cis-regulatory regions.
D. Both A and C
E. All of the above
Which of the following is NOT true for transcriptional regulation of eukaryotic genes?
A. There is one promoter region, but multiple cis-regulatory regions for a particular gene.
B. Multiple cis-regulatory regions of a gene either all equally activate transcription or all equally repress transcription.
C. The lariat structure generated during splicing is a component of complexes at cis-regulatory regions.
D. Both A and C
E. All of the above
U2 or U4 snRNA:
A. Spliceosome Ribozymes involved in mRNA processing
B. Carry out RNA interference as a means of post-transcriptional control.
C. Ribosome ribozymes involved in protein synthesis
D. RNA that codes for protein
E. None of the above
U2 or U4 snRNA:
A. Spliceosome Ribozymes involved in mRNA processing
B. Carry out RNA interference as a means of post-transcriptional control.
C. Ribosome ribozymes involved in protein synthesis
D. RNA that codes for protein
E. None of the above
Leucine zipper transcription regulators bind DNA with their repeated leucine stretch.
A. True
B. False
Leucine zipper transcription regulators bind DNA with their repeated leucine stretch.
A. True
B. False
Repressors or activators of alternative splicing bind directly to:
A. Spacer DNA
B. Cis-regulatory sequences
C. Intron consensus sequences
D. Promoter region
E. None of the above
Repressors or activators of alternative splicing bind directly to:
A. Spacer DNA
B. Cis-regulatory sequences
C. Intron consensus sequences
D. Promoter region
E. None of the above
More than one protein can be encoded from one gene by use of:
A. RNA editing
B. Protein phosphorylation
C. Alternative splicing
D. Both A and C
E. All of the Above
More than one protein can be encoded from one gene by use of:
A. RNA editing
B. Protein phosphorylation
C. Alternative splicing
D. Both A and C
E. All of the Above
Which of the following is a common motif found in transcriptional regulators?
A. They are transcription activators, but not transcription repressors.
B. They are involved in post-transcriptional or post-translational regulation of multiple genes.
C. They bind to cis regulatory sequences of multiple genes.
D. Both A and C
E. All of the above
Which of the following is a common motif found in transcriptional regulators?
A. They are transcription activators, but not transcription repressors.
B. They are involved in post-transcriptional or post-translational regulation of multiple genes.
C. They bind to cis regulatory sequences of multiple genes.
D. Both A and C
E. All of the above
mRNA:
A. Spliceosome Ribozymes involved in mRNA processing
B. Carry out RNA interference as a means of post-transcriptional control.
C. Ribosome ribozymes involved in protein synthesis
D. RNA that codes for protein
E. None of the above
mRNA:
A. Spliceosome Ribozymes involved in mRNA processing
B. Carry out RNA interference as a means of post-transcriptional control.
C. Ribosome ribozymes involved in protein synthesis
D. RNA that codes for protein
E. None of the above
Genes that are active in all cell types are expected to be found in constitutive heterochromatin regions of chromosomes.
A. True
B. False
Genes that are active in all cell types are expected to be found in constitutive heterochromatin regions of chromosomes.
A. True
B. False
Which is an expected characteristic of master transcription regulators?
A. They are transcription activators, but not transcription repressors.
B. They are involved in post-transcriptional or post-translational regulation of multiple genes.
C. They bind to cis-regulatory sequences of multiple genes.
D. Both A and C
E. All of the above
Which is an expected characteristic of master transcription regulators?
A. They are transcription activators, but not transcription repressors.
B. They are involved in post-transcriptional or post-translational regulation of multiple genes.
C. They bind to cis-regulatory sequences of multiple genes.
D. Both A and C
E. All of the above
A dimerized helix-loop-helix transcription regulator binds directly to:
A. Spacer DNA
B. Cis-regulatory sequences
C. Intron consensus sequences
D. Promoter region
E. None of the above
A dimerized helix-loop-helix transcription regulator binds directly to:
A. Spacer DNA
B. Cis-regulatory sequences
C. Intron consensus sequences
D. Promoter region
E. None of the above
miRNA (microRNA):
A. Spliceosome Ribozymes involved in mRNA processing
B. Carry out RNA interference as a means of post-transcriptional control.
C. Ribosome ribozymes involved in protein synthesis
D. RNA that codes for protein
E. None of the above
miRNA (microRNA):
A. Spliceosome Ribozymes involved in mRNA processing
B. Carry out RNA interference as a means of post-transcriptional control.
C. Ribosome ribozymes involved in protein synthesis
D. RNA that codes for protein
E. None of the above
A hypothetical Zinc-finger protein, we will call it protein-X, is active only in neurons. It is only active when phosphorylated. Which of the following statements is consistent with these facts?
A. The cis-regulatory sequences to which this protein-X binds, are regulating a gene that is transcribed only in neurons.
B. The "activity" of this protein X is its ability to bind specific DNA sequences.
C. This protein-X is the substrate of a kinase that is only active in neurons.
D. Both A and C
E. All of the above
A hypothetical Zinc-finger protein, we will call it protein-X, is active only in neurons. It is only active when phosphorylated. Which of the following statements is consistent with these facts?
A. The cis-regulatory sequences to which this protein-X binds, are regulating a gene that is transcribed only in neurons.
B. The "activity" of this protein X is its ability to bind specific DNA sequences.
C. This protein-X is the substrate of a kinase that is only active in neurons.
D. Both A and C
E. All of the above
How can an inhibitor/repressor protein carry out post-transcriptional control of gene expression?
A. An inhibitor/repressor can bind mRNA and inhibit movement from cytoplasm to the nucleus.
B. An inhibitor/repressor can bind mRNA and inhibit alternative splicing.
C. An inhibitor/repressor can bind transcription regulators at the cis-regulatory sequences.
D. Both A and C
E. All of the above
How can an inhibitor/repressor protein carry out post-transcriptional control of gene expression?
A. An inhibitor/repressor can bind mRNA and inhibit movement from cytoplasm to the nucleus.
B. An inhibitor/repressor can bind mRNA and inhibit alternative splicing.
C. An inhibitor/repressor can bind transcription regulators at the cis-regulatory sequences.
D. Both A and C
E. All of the above