Innate Immunity
Lymphatic System+Immunity
Immunoglobulins
Infection + other
SCID + pregnancy
100
promotes opsonisation, mast cell degranulation
What are the functions of C3b?
100
bone marrow and thymus
What are the primary lymph organs?
100
2 light chains and 2 heavy chains
What is the basic structure of an immunoglobulin?
100
A pathogen likely to be found in UTI's
What is Escherichia coli?
100
A placental hormone responsible for maintenance of the corpus leteum that also stimulates the release of testosterone by developing testes in XY embryos
What is human chorionic gonadotropin (hCG)?
200
Inflammation, Interferon, NK cells, Complement System
What are the components of innate immunity?
200
Gastrointestinal tract, Respiratory system and urogenital tracts
What are the locations of mucosal-associated lymphoid tissue (MALT)?
200
alpha heavy chain
What is the heavy chain of the IgA class of immunoglobulin?
200
Where T cell precursors migrate & differentiate
What is the Thymus?
200
Thin and clear mucous
What is the consistency of cervical mucus caused by elevated oestrogen levels?
300
Destroy virus infected cells through non-specifically released “perforin” that lyses cell membranes leading to induction of osmotic cell lysis or apotosis
What is the mechanism of action of NK cells?
300
The enhancement of phagocytosis
What is opsonisation?
300
It is the only class of Ig that crosses the placenta
What is a unique feature of IgG?
300
The causative parasite in Malaria
What is Plasmodium species?
300
selective stimulation of LH AND GnRH
What is the effect of a high level of oestrogen at pituitary gland and hypothalamus?
400
C5a, C6, C7, C8, C9
What are the components of the Membrane Attack Complex (MAC)?
400
The site where self tolerance, or the removal of self-reactive lymphocytes occurs
What is the bone marrow?
400
The first Ig to be made by the foetus as well as the first Ig made by virgin B cells
What is IgM
400
age, pregnancy, nutrition, illness, immunosuppresants, chemotherapy, stress
What are factors that increase susceptibility to infection?
400
0.001%
What is the percentage of sperm that make it to the fertilisation site (ampulla of oviduct)?
500
1.function as endogenous pyrogens (EP) to induce fever 2.decrease plasma iron by acting at liver, spleen 3. stimulate acute phase protein release; promoting inflammation, tissue repair and immune cell activity
What are functions of IL-1, IL-6 and TNF?
500
Site upon which antigen is presented by B cells
What is MHC Class II?
500
A short-term immunization by the injection of antibodies, such as gamma globulin, that are not produced by the recipient's cells.
What is Artificially acquired passive immunity?
500
A common histological and gross appearance of cell death in TB infection
What is Caseous necrosis?
500
The gene affected in X linked SCID
What is the IL2RG gene?
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