Activity 3- Quickfire
List the 3 lobes of the cerebellum
Anterior, posterior, flocculonodular
Compare the corticopontocerebellar pathway with the spinocerebellar (L-CST component) for the following:
Location(s) of the first neuron in each (cell body, not whole axon)
i. Ponto:
Sensory association areas
1. Name of output nuclei
a. Direct:
GPi and SNr
1. The region that provides the strongest input to respective regions (basal ganglia and cerebellum):
Spinal cord neurons for spinocerebellar and cortex (association areas+primary) for basal ganglia
1. The superior peduncle contains:
d. none of the above
The two fissures that separate the lobes of the cerebellum
Primary and posterolateral fissure
Compare the corticopontocerebellar pathway with the spinocerebellar (L-CST component) for the following:
a. Location(s) of the first neuron in each (cell body, not whole axon)
i. Spino:
Spinal Cord
1. Name of output nuclei
b. Indirect:
GPi and SNr
The thalamic nuclei part of each pathway:
VA/VL basal ganglia, VL cerebellar
2. The subthalamic nucleus:
d. all of the above
Which peduncle do the climbing fibers in the corticoolivocerebellar pathway enter through?
Inferior
Compare the corticopontocerebellar pathway with the spinocerebellar (L-CST component) for the following:
b. The peduncle each pathway uses to enter the cerebellum
Ponto:
Middle cerebellar peduncle
2. Neurotransmitters released by striatum
a. Direct:
GABA, SP
The glutamatergic neurons part of each pathway:
Basal Ganglia:
VA/VL, cortex
3. Glutamate is released by the following neurons:
c. granule cells
List the 4 cerebellar deep nuclei.
Dentate, emboliform, globose, and fastigial
Compare the corticopontocerebellar pathway with the spinocerebellar (L-CST component) for the following:
b. The peduncle each pathway uses to enter the cerebellum
ii. Spino:
Inferior
2. Neurotransmitters released by striatum
a. Indirect:
GABA, ENK
The glutamatergic neurons part of each pathway:
Cerebellum:
Spinal cord neuron, granule cell, E/G/F deep nuclei, VL thalamic nuclei
4. Loss of the SNc neurons in the direct pathway only would:
a. Produce excessive drive through the indirect pathway
List the four inhibitory neurons of the cerebellum.
Purkinje, stellate, basket, and Golgi
Compare the corticopontocerebellar pathway with the spinocerebellar (L-CST component) for the following:
c. The deep nuclei that are part of the pathway
i. Ponto:
Dentate
Effect of SNc and the neurotransmitter used
a. Direct:
b. Indirect:
a. Direct: excitatory, DA
b. Indirect: Inhibitory, DA
State where the following are located within the nervous system, making sure to be as exact as possible.
a. Granule cells
Granule layer in cerebellar grey matter
*Activity 4 pt. 1 question 2*
State where the following are located within the nervous system, making sure to be as exact as possible.
Deep nuclei:
Arbor vitae in cerebellum