Chapter 12
This type of cell is a connective tissue cell that contains heparin and histamine.
Mast cells
The physician would like your recommendation for a drug to give your CF patient with chronic Pseudomonas infections. What would be the best recommendation?
What is Tobramycin
β-lactam antibiotics exert their pharmacologic activity by:
a) Inhibiting translation of RNA into proteins
b) Inhibiting cell wall synthesis
c) Inhibiting protein synthesis
d) Inhibiting DNA synthesis
b) Inhibiting cell wall synthesis
Which of the following agents is useful in the presence of an irritating, persistent, nonproductive cough?
a. Antitussive
b. Expectorant
c. Mucolytic expectorant
d. Sympathomimetic
a. Antitussive
How is Cromolyn Sodium is effective in preventing bronchospasm?
What is by inhibiting mast cell degranulation (mast cell stabilization).
What is the approved dose of pentamidine by aerosol for prevention of PCP?
What is 300 mg once every 4 weeks.
The most common adverse reaction to penicillin is:
a) Headache
b) Nausea
c) Hypersensitivity
d) Seizures
c) Hypersensitivity
NO is considered a:
a) Nitrovasodilator
b) Systemic vasodilator
c) Coronary vasodilator
d) Cerebral vasodilator
a) Nitrovasodilator
What is the most commonly reported side effect of cromolyn sodium?
What is nasal congestion.
A patient newly diagnosed with cystic fibrosis is brought to the emergency department with complaints of voice alterations. Her medication list includes TOBI, albuterol, and hypertonic saline. Which medication is most likely causing this complaint?
TOBI
Which of the following common pathogens are NOT responsible for community-acquired pneumonia?
a) Haemophilus influenza
b) Chlamydia pneumoniae
c) Staphylococcus
d) Mycoplasma pneumoniae
c) Staphylococcus
The best expectorant for a cold is:
a) Water
b) Terpin hydrate
c) Guaifenesin
d) Glycerol
c) Guaifenesin
Leukotrienes exhibit which of the following effects? (Choose all that apply)
1. Increased mucus secretion
2. Increase ciliary action
3. Increased airway edema
4. Bronchoconstriction
5. Recruitment of antiinflammatory cells into airways
What is 1, 3, and 4
An 8-year-old patient is brought to the pediatrician’s office with the complaint of uncomplicated flulike symptoms for 1 day. The pediatrician asks you to suggest an inhaled antiinfective. Which medication is the most appropriate at this time?
Zanamivir
Your patient has just been diagnosed with TB. The Doctor has started the patient on a antimicrobial therapy regimen that includes 4 different drugs. Which of the following is the most likely regimen the patient was started on?
a) Ribavirin, Isoproterenol, Pentamidine, Epinephrine
b) Rifampin, Isoniazid, Pyrazinamide, Ethambutol
c) Ribavirin, Isoniazid, Pyrazinamide, Ethambutol
d) Rifampin, Isoniazid, Pentamidine, Ethambutol
b) Rifampin, Isoniazid, Pyrazinamide, Ethambutol
What property of sympathomimetic decongestants results in vasoconstriction?
a) α1
b) β2
c) β1
d) H1
a) α1
Which of the following are antileukotrienes (select all that apply): 1. Zafirlukast 2. Zileuton 3. Cromolyn sodium 4. Montelukast 5. Nedocromil sodium
What is 1, 2, and 4
Precautionary measures that are suggested when administering pentamidine to reduce the risk of both drug exposure and tuberculosis (TB) infection include (select all that apply):
1. Use a nebulizer system with one-way valves and expiratory filter.
2. Administer aerosol in a negative-pressure room.
3. Do not expose pregnant women and nursing mothers to the drug.
4. Use barrier protection.
5. Stop nebulization if the patient takes the mouthpiece out of the mouth.
What is 1, 2, 3, 4, and 5
Ventilator-associated pneumonia (VAP) has been successfully treated with aerosolized (SELECT ALL THAT APPLY):
1. Cephalosporins
2. Gentamicin
3. Tobramycin
4. Quinolones
5. Penicillin
2 & 3
Gentamicin & Tobramycin
The approved dose (10mg) of which sympathomimetic decongestant has been found to have little to no effect on nasal decongestion?
a) Phenylephrine
b) Pseudoephedrine
c) Codeine Sulfate
d) Diphenhydramine HCl
b) Pseudoephedrine