SABAs
what does SABAs stand for and the name of medications
Short-acting β-Adrenergic agonists
Albuterol (Inhaler or nebulizer)
What does SAMA stand for?
What is the trade/generic name?
Short-Acting Muscarinic Antagonist
Generic: Ipratropium
Trade: Atrovent
what does LABAs stand for?
Generic & Trade names
Long-acting β2-Adrenergic Agonist Drugs
Generic: Formoterol
Trade: Foradil
what does LAMAs stand for?
Generic & Trade names
Long Acting Muscarinic Anticholinergics
Generic: Tiotropium bromide
Trade Spiriva
what are the types of steroids? (P,F,B,M)
which ones are inhaled, PO, or IV ?
Prednisone (Oral) * pred can cause preg w/BC
Fluticasone (Inhaled) *flute can be blown into
Budesonide (Inhaled) *Bud is inhaled
Methylprednisolone (IV) *inject meth
How does it work?
What cells does it inhibit?
When to use
Long-term or short-term?
Relieves acute bronchospasms/bronchodilation
prevent release of mast cells
Acute/severe attacks
Short-term/PRN/as needed
How does it work?
When to use
Long-term or short-term?
Bronchodilation, prevent tightening around bronchi.
Acute asthma attacks, PRN COPD
Short - term
How does it work and how long does it last?
Long-term or short-term?
relaxes smooth muscles in airways (12 hrs)
Long term
How does this medication work?
What receptor does it target and what does that receptor do?
Bronchodilates & reduces mucus
Targets Muscarinic that is responsible for contraction of smooth airway muscles
How does it work?
Is this medication long term, short term or both?
reduces hyperresponsiveness of lungs/stops migration of mast cells
Most effective as long term
Side Effects (5)
Tremors, anxiety, tachycardia, palpitations, nausea, increased blood pressure
Side effects (5)
Headache, dry mouth, dizziness, palpitations, see halos, vision changes
Can this medication be used alone?
NO
Long term or short term medication
Is it for asthma, COPD or both?
Long term
Both
MUST KNOW SIDE EFFECTS (6)
oral thrush, osteoporosis, increased blood sugar, Increased blood pressure, easy bruising, vision changes, cataracts (halos)
COPD medication
Asthma medication
or
Both
Both
COPD medication
Asthma medication
or
Both
Both
what other type of drug can this be used with and the medication it converts to?
LABA + ? = ?
Corticosteroids (Budesonide)
LABA + ICS = Symbicort
Formoterol + Budesonide = Symbicort
ICS + LABAs side effects ( 4)
throat irritation, headaches, GI issues, tremors, increases Blood pressure, muscle weakness, increased upper respiratory infection susceptibility and sinusitis
what do we need to promote when taking this medication?
what helps reduce side effects?
BONE HEALTH (ca, Vit. D, weight bearing exercises)
wash out mouth with H2O
what other type of drug can this be used with and the medication it converts to?
SABA + ? = ?
Short-Acting Anticholinergic drugs (SAMAs): Ipratropium
SABA + SAMA = Combivent, DuoBeb
Albuterol + Ipratropium (Atrovent) = Combivent, DuoBeb
Trade and Generic name of SAMAs
Generic : Ipratropium
Trade: Atrovent
How does ICS + LABAs work?
bronchodilation
reduces inflammation
relaxes muscles around airways
What do Leukotriene modifiers do?
What are the generics and trade names?
What white blood cells do they target?
Prevent bronchoconstriction from mast cells, mucus secretion and oedema.
Generics (trades)
Montelukast (siingulair)
Zafirlukast (Accolate)
Zileuton (Zyflo)
Reduces eosinophils limiting inflammatory damage in airways.
What medication(s) is this combined with?
what do the combined medication(s) conver to?
ICS + ? + ?
LABAs and Leukotriene Modifiers
ICS + LABAS = Symbicort
Budesonide + Formoterol = symbicort