Anime
This anime features the Straw Hat Pirates.
One piece
American politician bald head.
JD Vance
This video game references the roleplaying game Dungeons and Dragons.
Baldur's gate
This is the person that directed Titanic (1997)
James Cameron
This type of cell helps the body fight infections.
White cell
This food is adored by the Death Note character Ryuk.
Apples (although the full explanation for that is not shown in the anime)
This was the funny number that started the 2025 number meme revolution
67
This top rated indie game allows players to escape city life, restore a run-down farm, and form friendships with the townspeople.
Stardew valley
This is what the Infinity gauntlet is used for.
Controlling the infinity stones.
This molecule contains genetic information.
DNA / ADN (dezoxiribonucleic acid)
This was the first anime movie that studio Ghibli produced.
Castle in the sky (1986)
A bat with a bat.
Tung tung tung sahur
This is what NPC stands for.
Non-playable character
This person is the composer for Interstellar's soundtrack.
Hans Zimmer
This structure conects muscles to bones.
Tendon
This anime is the one that popularized Isekai tropes.
Sword Art Online. (Isekai refers to the transport of the protagonist into another realm or world)
This emoji meme resurfaced in 2025
Skull emoji.
This is the video game that made raytracing mainstream.
Cyberpunk 2077
This is the name of the AI in 2001:Space Odyssey (from 1968)
HAL 9000 (the main antagonist)
This is the objective of the CRISPR method.
Gene editing
This is the full name of the person who said "The world is cruel, but also very beautiful." in one of the most popular anime of all time.
Mikasa Ackerman (from Attack on Titan)
This is the boxer who broke Jake Paul's jaw in 2 places giving us a meme format to stay.
Joshua Anthony
Half-Life 2; Half-Life 2:Episode 1; Half-Life 2: Episode Two; Team Fortress 2; Portal, were the games included in this bundle from 2007.
The orange box
This is the longest running movie franchise in movie history.
James Bond
This animal was the most commonly used organism in the early days of genetic research.
Fruit fly (Drosophila Melanogaster)