Alphabet Soup
Treatments
Its Always Lupus
Diagnosis
Randos
100
anti-dsDNA
SLE
100
first line treatment for Temporal arteritis
Prednisone (typically 1mg/kg/day)
100
Lupus increases risk factors for what
CAD and malignancy
100
Osteoarthritis
history and physical
Xray is confirmatory
100
Hilar adenopathy
Sarcoid
200
anti-CCP
rheumatoid arthritis
200
1st line for RA
Methotrexate
200
type of anemias in lupus
normocytic, normochromic anemia of inflammation, AIHA in 10%, lymphopneia/leukopniea (mild), thrombocytopenia
200
Calcium Pyrophosphate Deposition
rhomboid-shaped and positively birefringent (blue when parallel to and yellow when perpendicular to the polarizing axis of an optical filter)
along with leukocytes
200
Most common extrapulmonary manifestation of Sarcoid
erythema nodosum
300
anticentromere
limited cutaneous systemic sclerosis or CREST
300
Mainstay tx for Lupus
Hydroxychloroquine
300
medication adverse effects of HCQ
GI intolerance, blurry vision, retinopathy, myopathy
300
myositis
muscle biopsy
300
widespread chronic pain, fatigue, disturbed sleep, and mental fogginess
fibromylagia
400
antihistone
drug-induced SLE
400
Tx for eosinophilic granulomatosis with polyangitis (besides steroids and better than cyclophosphamide)
mepolizumab
400
malar (butterfly rash)
400
Name 3 out of 7 for RA dx
1. Morning stiffness lasting longer than one hour 2. At least 3 joint areas affected 3. At least one affected joint in hand 4. Arthritis is symmetric 5. Presence of rheumatoid nodules 6. Serum rheumatoid factor 7. Radiologic changes on hand and wrist x rays.
400
vasculitis with PAINFUL oral and genital ulcers
Behcet's syndrome
500
anti-U1-RNP
mixed connective tissue disease
500
mixed connective tissue disease treatment
tx depends on tissue specific manifestations.
Vasodilators for PAH and Raynaud
PPI for esophageal disease
500
best time to consider pregnancy in patient with lupus
6 months with well controlled disease
500
Sjorgren diagnosis
Presence of subjective finding of Sjögren syndrome (e.g., sicca) plus any combination of the following resulting in a score of ≥4:
Salivary gland biopsy specimen showing ≥1 foci of lymphocytic infiltrate/4 mm2
3
Anti-Ro/SSA autoantibodies
3
Ocular staining score ≥5 in at least one eye
1
Schirmer test ≤5 mm/5 min in at least one eye
1
Unstimulated whole saliva flow rate ≤0.1 mL/min
1
500
fever with daily evening spikes, salmon colored macular or maculopapular rash
Adult onset still