Alphabet Soup
Big Pharma
Picture Perfect
Oh, my aching back!
Say what?
100
anti-dsDNA
What is SLE
100
Gold standard therapy for RA.
What is methotrexate
100
See powerpoint.
What is malar (butterfly) rash. Associated with SLE.
100
Pain and swelling in multiple joints, morning stiffness lasting at least 1 hour, no DIP involvement
What is rheumatoid arthritis
100
sinus issues, epistaxis, hearing loss, lung infiltrates/nodules, hemoptysis, glomerulonephritis, palpable purpura; c-ANCA/anti-PR3 positive
What is granulomatosis with polyangiitis (Wegener's)
200
anti-CCP
What is rheumatoid arthritis
200
The American College of Rheumatology recommends this type of NSAID for patients over 75 years old.
What is topical NSAIDs (ex: diclofenac)
200
See powerpoint.
What are Heberden nodes (DIP). Associated with osteoarthritis. Bouchard's nodes are the same thing but at PIP joints.
200
Low back stiffness and pain that spreads to buttocks, worse in morning; more common in men in second and third decade; stooped posture with limited mobility of spine and chest
What is ankylosing spondylitis
200
associated with hepatitis B infection; constitutional symptoms, renal failure, hypertension, abdominal pain after eating, mononeuropathy, livedo reticularis, purpura, painful subcutaneous nodules
What is polyarteritis nodosa
300
anticentromere
What is limited cutaneous systemic sclerosis or CREST
300
True or False? In a patient with recurrent gout that has had hypersensitivity reaction to allopurinol, febuxostat is a safe alternative for urate lowering therapy.
True.
300
See powerpoint.
What is shawl sign. Associated with dermatomyositis.
300
polyarticular arthritis, possible axial involvement, DIPs usually involved, dactylitis ("sausage fingers"), nail pitting, characteristic rash, "pencil-in-cup" deformity on plain films
What is psoriatic arthritis
300
constitutional symptoms, arthralgias/myalgias, cool extremities, arm/leg claudication, syncope, blood pressure differences between arms, asymmetric arterial pulses in arms and legs; affects mostly young women
What is Takayasu arteritis
400
antihistone
What is drug-induced SLE
400
True or False? In RA, if there is no symptomatic improvement with a TNF-alpha inhibitor, addition of abatacept has been shown to improve efficacy.
False.
400
See powerpoint.
What is sclerodactyly. Associated with systemic sclerosis.
400
postinfectious arthritis, urethritis, conjunctivitis
What is reactive arthritis
400
history of allergic rhinitis, nasal polyps, asthma; lung infiltrates, peripheral neuropathy, hypereosinophilia
What is eosinophilic granulomatosis with polyangiitis (Churg-Strauss)
500
anti-U1-RNP
What is mixed connective tissue disease
500
Nonbiologic DMARD associated with bladder cancer, lymphoma, and other malignancies
What is cyclophosphamide
500
See powerpoint.
What is relapsing polychondritis
500
acute painful inflammatory arthritis, cartilage calcification on xray, synovial fluid showing rhomboid, positively birefringent crystals
What is acute CPP crystal arthritis (pseudogout)
500
abdominal pain, palpable purpura (typically on palms/soles), arthritis; skin biopsy showing leukocytoclastic vasculitis, IgA deposition; all symptoms started after upper respiratory infection
What is Henoch-Schonlein purpura
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