Physiology
RYTARY
Parkinson's
100
What is the difference between extended and immediate release drugs?
Extended release: continues to have the drug released in the GI tract Immediate release: all released when it reaches the GI tract
100
Could a dosage of RYTARY lower than 145 mg still benefit a patient?
Yes
100
What type of tremor do PD patients usually have?
Rest
200
What is the effect of not having enough dopamine on the indirect pathway?
Inability to stop a movement
200
Which dosages of RYTARY were effective? (145mg, 245mg, 390mg)
All dosages (145mg, 245mg, 390mg)
200
Name three symptoms of PD.
Bradykinesia, tremor, rigidity, shuffling gait, bent over gait, smaller writing, changes in speech, decreased balance, decreased coordination, freezing gait, decreased arm swing
300
What is the protein that accumulates to form a Lewy Body?
Alpha Synuclein
300
What date was RYTARY approved by the FDA?
January 7, 2015
300
What are the four things that the UPDRS evaluates?
Cognitive function, ADLs, Motor function, and complications with therapy
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