What model organism was used for these experiments?
Mice!
A cluster of interneurons in the respiratory CPG responsible for generating respiratory rhythm in mammals
pre-Bötzinger complex (PBC)
The method used to record extracellularly
suction electrode
What effect did CNQX have on PBC neuron rhythms?
It abolished them
The authors come from institutions in these three countries
Sweden, France, and Japan
A recombinase enzyme that cuts out the sequence between two loxP sites
Cre
Vglut2f/f;PCre mutants have malformed and reduced numbers of synaptic vesicles at what kind of synapse?
asymmetric synapses
The method used to observe individual currents in the neurons
Voltage clamp
The three glutamate receptors
AMPA, Kianate, NMDA
A CPG that VGLUT2 does NOT affect
the locomotor CPG
Method that uses antibodies labeled with fluorescent dyes in order to visualize proteins
Immunofluorescence
AMPA/Kainate receptor antagonist
CNQX
The nerve root recorded from
hypoglossal nerve root
The two types of receptor that bicuculline and strychnine antagonize
GABAa and glycine receptors
The name for the bluish discoloration resulting from poorly oxygenated blood that mutant pups experienced
cyanosis
Method used to identify Vglut2 mRNA
in situ hybridization
Where the PBC is located
the medulla of the brainstem
The synaptic current mediated by AMPA/kianate (slow or fast)
Fast
What bodily fluid were drugs diluted in?
CSF
A referendum to repeal Legislative Document 798, which aims to eliminate religious and philosophical exemptions from vaccination against certain communicable diseases for K-12 and college students and employees of healthcare facilities and nursery schools
Maine Question 1 on the March 3 ballot!