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A primary care provider wishes to start a tricyclic antidepressant to treat neuropathic pain and comorbid insomnia in a 67 yo Alaska Native woman. Which option is best?
A. Nortriptyline, because it is less anticholinergic than amitriptyline
B. Amitriptyline, because it does not carry the risk of prolonged QT syndrome
C. Nortriptyline, because it has a shorter elimination half-life than amitriptyline
D. Amitriptyline, because it is not dangerous on accidental overdose
A. Nortriptyline, because it is less anticholinergic than amitriptyline