What is the dome-shaped muscle under your lungs that helps you breathe by moving up and down?
Diaphragm
What jelly-like substance fills the cell and holds organelles in place?
Cytoplasm
What was the system of land ownership and duties between lords and vassals called in medieval Europe?
Feudal System
Which American novel written by Harper Lee features a young girl named Scout Finch and her father, Atticus, a lawyer?
To Kill a Mockingbird
Which artist is famous for painting water lilies in a garden at Giverny?
Claude Monet
Which president of the United States was from Independence, Missouri?
Harry S Truman
What is the name of the tiny air sacs in the lungs where gas exchange happens?
Alveoli
Which organelle is known as the “powerhouse” of the cell because it releases energy from food?
Mitochondrion (plural: Mitochondria)
What were the series of religious wars launched by European Christians to capture the Holy Land called?
Crusades
Which fictional detective created by Sir Arthur Conan Doyle is known for using sharp observation and logic to solve mysteries with Dr. Watson?
Sherlock Holmes
What is the name of the sculpture of a man thinking, created by Auguste Rodin?
The Thinker
Which 19th‑century author from Missouri wrote The Adventures of Tom Sawyer and Adventures of Huckleberry Finn?
Mark Twain (Samuel Clemens)
Which endocrine gland in the neck helps regulate metabolism by releasing thyroxine?
Thyroid
What is the large, water-filled sac in plant cells that stores materials and helps keep the cell firm?
Central Vacuole
Which document, signed by King John of England in 1215, limited the king’s power?
Magna Carta
Which English author, who never married but often wrote about love, is famous for the novel Pride and Prejudice?
Jane Austen
Which American Pop artist created bright screen prints of soup cans and celebrities?
Andy Worhol
Which St. Joseph‑to‑California mail service began in 1860 and made Missouri a key starting point for fast riders?
Pony Express
Which system makes hormones that help control growth, mood, and metabolism?
Endocrine System
Which folded cell membrane network handles protein processing (with ribosomes) and lipid synthesis/detox when smooth?
Endoplasmic Reticulum
Which battle in 1066 led to Norman control of England under William the Conqueror?
Battle of Hastings
Which novel by William Golding follows a group of boys stranded on an uninhabited island as their society breaks down into chaos?
Lord of the Flies
What is the title of the painting by Grant Wood that shows a farmer holding a pitchfork next to his daughter?
American Gothic
What violent pre–Civil War conflict along the Missouri–Kansas border featured raids by “Border Ruffians” and “Jayhawkers”?
Bleeding Kansas (Border War)
Which part of the nervous system controls involuntary actions like heart rate and digestion?
Autonomic Nervous System
What organelles contain digestive enzymes that break down waste, old organelles, and invading particles?
Lysosomes
Which empire preserved Roman and Greek learning in its capital of Constantinople during the Middle Ages?
Byzentine Empire
Which Old English epic poem, written by an anonymous author, tells the story of a hero who defeats the monster Grendel and later fights a dragon?
Beowulf
Which Italian artist of the early Renaissance painted The Birth of Venus, showing a goddess standing on a shell?
Sandro Botticelli
What was the name of the 1857 Supreme Court case involving an enslaved man from St. Louis who sued for freedom?
Dred Scott vs. Sandford