General Overview
Localized Scleroderma Types
Systemic Scleroderma Types
Diagnosis & Causes
Treatment & History
100

This autoimmune disease affects about 250 out of every 1,000,000 people.

What is scleroderma?

100

This subtype presents as discolored patches of skin that grow during active periods and flatten with treatment.

What is circumscribed morphea?

100

This is the most common form of systemic scleroderma and primarily affects fingers, forearms, and the face.

What is limited scleroderma?

100

This medical specialty typically manages scleroderma diagnosis and treatment.

What is rheumatology?

100

This class of medications may be used to suppress the immune system and slow disease progression.

What is chemotherapy (or chemotherapy infusions)?

200

These are the two bodily systems most affected by systemic scleroderma.

What are the skin and internal organs?


200

Defined as having four or more areas of thickened skin, this subtype is more widespread.

What is generalized morphea?

200

People with limited scleroderma commonly experience Raynaud’s, GI problems, and this type of pain.

What is musculoskeletal pain?

200

This test involves removing and analyzing a small piece of affected skin.

What is a biopsy?

200

This type of medication is commonly prescribed to help manage severe tissue or organ-related pain.

What are pain medications?

300

These are the two main categories of scleroderma.

What are localized and systemic?

300

This subtype forms thick, tight bands that may affect deeper tissues like muscle and bone.

What is linear scleroderma?

300

This severe form involves excess collagen production and can be life-threatening when it affects the lungs or heart.

What is diffuse scleroderma?

300

These imaging tests may be used to detect deep tissue or organ involvement. Name one.

What is a CT scan or an X-ray?

300

Although treatments can slow progression, there is currently no cure for this hallmark feature of scleroderma.

What is skin thickening?

400

This category only affects the skin and can appear anywhere on the body.

What is localized scleroderma?

400

Linear scleroderma can impact this part of the musculoskeletal system, potentially causing scoliosis.

What is the spine?

400

This subtype causes internal organ disease without any skin thickening.

What is sine sclerosis?

400

The thickened skin seen in scleroderma is due to overproduction of this protein.

What is collagen?

400

The first detailed description of scleroderma was written in the mid-1700s by this individual.

Who is Carlo Curizo?

500

This form affects the skin, major blood vessels, and organs.

What is systemic scleroderma?

500

This subtype is most connected to movement restrictions and under-development of affected areas.

What is linear scleroderma?

500

Of the three systemic subtypes, this one is associated with the greatest risk of major organ damage.

What is sine scleroderma?

500

The current understanding is that scleroderma is caused by issues in this body system, possibly influenced by genetics.

What is the immune system?

500

This person first used the term “scleroderma” in 1836.

Who is Giovambassita Fanotonetti?

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