The Basics
These cells are special and are able to create more of themselves, or develop into other special cells.
What are Hematopoietic stem cells
Patients that are able to donate their own stem cells, will receive this type of hemopoietic stem cell transplant.
What is Autologous HSCT
Petechiae, purpura, bruising, bleeding at puncture sites
Plt count less that 10,000
What is Thrombocytopenia
Identical twin donation
Syngeneic HSCT
Day 0
what is Transplant day
This lineage of cells are called the "first responders."
What is Myeloid Lineage
This type of stem cell transplant uses a donated stem cells.
What is Allogenic HSCT
ANC < 0.5
What is Neutropenia
Sibling donor, full HLA match
what is Match related donor
The process of collecting stem cells
Apheresis
All blood cells live in the ___________.
What is Bone Marrow
This type of stem cell transplant can be given to treat Sickle Cell and Aplastic Anemia
What is Allogenic HSCT
Most common complication during transplant leading to death
What are infections
DAILY DOUBLE!
HLA Stands for this.
What is Human Leukocyte Antigen
After a stem cell transplant, what term is used to describe the process when transplanted stem cells start to produce new blood cells in the recipient's body?
What is engraftment
After a stem cell transplant, what labs should be monitored?
What are blood counts
The Disadvantages of the transplant are risk of tumor contamination and lack of graft vs tumor effect
What is Autologous HSCT
DAILY DOUBLE!!
Normally due to infection this is a life threatening condition of circulatory failure, causing inadequate oxygen delivery to meet cellular metabolic needs.
What is Septic Shock
Donated cells from a parent, child, or sibling
What is Haploidentical HSCT
Prior to a stem cell transplant, patients may undergo a high-dose treatment to eradicate diseased cells. What is this pre-transplant treatment called?
what is conditioning regimen
The traditional way that stem cells were collected
What is Bone marrow aspiration
This type of stem cell transplant offers the advantages of early engraftment, no GVHD and less risk of adverse effects.
What is Autologous HSCT.
This is a potential complication of an allogenic stemcell transplant where the donor's immune cells attack the recipient's body. Symptoms include skin rashes, GI issues, and liver dysfunction.
What is Graft Vs Host Disease or GVHD
HLA markers are used/recognized by this body system
What is the immune system
This process involves replacing a patients bone marrow with healthy stem cells.
What is stem cell transplant