Systemic
A disease which causes itchiness (especially during end stages) due to toxin build up (Urea and nitrogenous compounds), mineral imbalance and causing secondary hyperparathyroidism.
Chronic Kidney Disease
A disease which can be autoimmune or acquired. Causes itchiness as a result of neuropathy, dry skin or being more prone to infections and poor wound healing.
Diabetes (Type 1 or 2)
Condition characterised by hypoxic damage to the brain
Stroke
A psychotic disorder that sometimes presents with tactile hallucinations of insects under skin
Schizophrenia
Class of meds that reduce cholesterol
Statins
A broad category of disease which causes itchiness due to bile salt accumulation, dry skin and inflammation
Liver Disease -- especially ones causing cholestasis:
primary biliary cholangitis, primary sclerosing cholangitis, alcoholic liver disease, drug induced liver injury , viral hepatitis, NAFLD
Increased metabolic activity caused by this condition leads to increased blood flow which leads to flushing, warm and sensitive skin which becomes more reactive and can lead to itching
Hyperthyroidism
Broad term for damage of nerves not within the brain or spinal cord. Has multiple underlying causes.
Peripheral neuropathy
Causes: Diabetic neuropathy, Alcohol abuse, Infections (HIV, Varicella Zoster Virus), Autoimmune (Rheumatoid Arthritis, Guillain-Barré) etc.
Group of cancers characterised by abnormal lymphocytes.
Lymphoma
Common class of pain killer which has a high potential for addiction
Opioids
Low production of a hormone caused by this state, leads to the skin being poorly able to retain moisture leading to skin dryness and itching.
Hypothyroidism
"Disseminated in space and time"
Multiple Sclerosis
Infestation by an ectoparasite. A pathognomonic sign is burrows in the skin
Scabies
Class of medications which block flow of calcium ions into cardiac and smooth muscle cells
Calcium Channel Blockers
A Pathological condition where the stimulus-response curve that governs normal sensation has become distorted - resulting in itch which is out of proportion or even independent of an itch stimulus.
Neuropathic Itch
A delusional disorder characterised by infestation of parasites in the skin
Delusional Parasitosis (Ekbom Syndrome)
Class of antihypertensives that work by inhibiting an enzyme primarily produced in the lungs
ACE-inhibitors
This chronic condition is characterised by a neoplasm in the bone marrow leading to myeloproliferation which leads to erythrocytosis, thrombocytosis and leukocytosis.
This condition can lead to acute leukaemia
Polycythaemia vera