People of the Investigation
Science & Discovery
The Setting
Disease & Symptoms
Mysteries & Ethics
100

Who led the U.S. Army’s yellow fever commission?

Walter Reed

100

What question were the scientists trying to answer?

What causes Yellow Fever

100

Where did the investigation take place?

Cuba

100

Name one symptom of yellow fever.

Fever, chills, vomiting, etc

100

Why did scientists risk infection?

To find the truth and save lives

200

Which doctor first suggested mosquitoes carried yellow fever?

Carlos Finlay

200

What insect spreads yellow fever?

Mosquito

200

Why was yellow fever common there?

Hot, humid climate and standing water


200

What body change gives yellow fever its name?

Yellow skin/eyes
200

Why was using human volunteers controversial?

They could die or get sick

300

Which volunteer scientist died after being bitten by a mosquito?

Jesse Lazear

300

 What method did Reed’s team use to test Finlay’s theory?

Human experiments with mosquito bites

300

What made Havana dangerous for disease?

Unsanitary conditions and mosquitoes breeding

300

What organ does yellow fever damage?

The liver

300

What does “informed consent” mean?

Volunteers knew the risks and agreed

400

Who continued experimenting even after becoming ill?

James Carroll
400

Why were volunteers needed?

To prove mosquitoes transmit the disease

400

How did they control the spread after discovery?

Drained water, used nets/screens

400

Is yellow fever contagious by touch?

No

400

Why was Finlay not believed at first?

 His theory lacked proof and sounded odd

500

Who helped collect evidence and run experiments in Cuba?

Aristides Agramonte

500

What was the team’s most important discovery?

Yellow fever is spread by mosquitoes, not direct contact

500

What year did major experiments take place?

1900

500

What modern tool prevents yellow fever?

Vaccine

500

How did this investigation change medical research?

It improved ethics and testing methods

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