this phenomenon is known as either as a seizure last > 5 mins or two or more discrete seizures between which there is incomplete recovery of consciousness
What is status epilepticus?
Absence seizures occur at this frequency on EEG
What is 3 Hz?
these are the first aid steps which should be administered to a person who is experiencing a seizure
1. time: should be < 5 mins
2. move person to their side
3. remove nearby object that could be injurious
***DO NOT place anything in person's mouth
this drug works as a T-type calcium channel blocker and is the first-line treatment for absence seizures
What is ethosuximide?
These are the AED drugs that carry the highest risk for SJS/TEN & DRESS
1. phenobarbital
2. phenytoin
3. lamotrigine
4. carbamazepine
aware (simple partial) or impaired awareness (complex partial) are the two subcategories of this main seizure type
What is a focal seizure?
febrile seizures are most commonly seen in this popultion of individuals
What are children?
Benzos are the first line treatment for this epileptic state
What is status epilepticus?
*BONUS: what do you use if benzos don't work?
this is the most teratogenic of all the AEDs
What is valproate?
In addition to a Na+ channel blockade, this drug also blocks NDMA glutamate receptors
What is topiramate?
Absence seizures can be clinically classified in this way (i.e. another way of naming them)
these are the most common cause of seizures in adults vs elderly
adults: stroke, trauman, metabolic, infection
elderly: stroke, degenerative disease, tumor
Who should be selected to undergo epilepsy surgery?
1. pts with refractory epilepsy
2. pts with frequent, disabling seizures
3. pts with high risk of SUDEP
AEs of these drugs include sedation, ataxia, vertigo, and peripheral edema
What are gabapentin and pregabalin?
this drug, that can also be used for bipolar disorder and trigeminal neuralgia can cause hyponatremia via SIADH and blood dycrasias as its AEs
What is carbamazepine?
a partial seizure originates from a paroxysmal discharge in a focal area in this part of the cortex
What is the temporal lobe?
seizures due to a glucose issue can mimic this broad category of seizures
What are focal seizures?
This is the target for DBS in epilepsy
What is the anterior thalamic nucleus?
this is the deug of choice for status epilepticus due to the anticonvulsant effects lasting > 6hrs
What is lorazepam?
this is the most notable AE associated with levetiracetam
What are neuropsych effects?
electrical discharges in a primary generalized seizure originate from this specific area of the brain
What is the diencephalic activating system?
answer #1
these are the 4 major factors that put a person with epilepsy at risk for SUDEP
1. generalized tonic clonic seizures
2. nocturnal seizures
3. poststital respiratory depression
4. uncontrolled epilepsy
This drug has the following MOA:
SV2A synaptic protein ligand
What is levetiracetam?
gingival hyperplasia and purple glove syndrome are two of the many AEs that this drug can produce
What is phenytoin?