Midas Test
324
How many genes are interrogated on F1 CDx?
Two tubes
TMB, MSI, PDL1
What are three biomarkers of response to immunotherapy?
Ten + 1 H&E
What is the number of slides needed for F1CDx testing?
Loves Ramen
Who is Ben?
Base subs, Indels, CNA, Rearrangements
What are the 4 classes of genomic alterations identified by F1 testing?
RNA
What is unique to F1H testing?
~ 1 million base pairs
What is the size of sequencing data needed to accurately predict TMB/correlate with WES?
30%
What is the optimum % tumor DNA input needed for F1CDx testing?
Bartered for the Queen Sweden
Who is Ramon?
120 times more
What is the number of samples used for validation of F1CDx vs what is typical?
24 hours
How soon after blood or bone marrow aspirate do we need to start testing on F1H fresh specimen?
IHC
What is the methodology used for PDL1 testing?
25 mm squared
What is the minimum surface area for F1CDx slides/block submission?
I'm a rock star.
Who is Alexy?
Genomic findings, pertinent negatives, therapies and clinical trials.
What are key components of the F1CDx report?
70
How many genes are interrogated on F1L?
100 viable tumor cells
What is the minimum tumour cell content required for IHC testing?
1 mm cubed
What is recommended tissue volume for F1CDx?
Does a scientific blog and travel blog
Who is Hang?
Single gene, hotspot NGS, CGP
What are three approaches to molecular testing?
Non-invasive, tumor heterogeneity, resistance mutations
Germline variants, predicted drivers, polymorphisms
What are removed from the calculation of TMB?
Decalcified
What is a barrier to running bone specimen?
We share a birthday.
Who are Deborah Mukherjee and Sandro Cesaro?