Two Generals
Sepsis
Sepsis takes and gives
Septic Tank
EGDT
100
Temperature >38 C and Respirations > 20
What are two SIRS criteria?
100
Known or suspected infection and 2 or more SIRS criteria
What is Sepsis?
100
210,000
What are the number of deaths annually from sepsis?
100
Perfusion
What is the main problem in sepsis?
100

Sepsis "TAKE THREE" 

Lactate

Blood culture 

Output 

200
Heart rate > 90 and altered level of consciousness
What are two SIRS criteria?
200
Alcoholics, untreated GI disease, the elderly
Who is at risk for Sepsis?
200
10th
What is the ranking of sepsis deaths compared to other deaths in the US?
200
Gram Negative Baceria Gram Positive Bacteria Fungi Viruses
What the causative microorganisms of sepsis?
200
Start an antibiotic within 1 hour
What is part of the sepsis EGDT?
300
WBC count > 12,000 or < 4,000 and >10% bands
What are two SIRS criteria?
300
immune/inflammatory response is not localized to area around antigen
What is the body's response in sepsis?
300
25-50%
What is the mortality from severe sepsis and septic shock?
300
Altered Level of consciousness
What is a SIRS criteria?
300
Central line placed within 2 hours
What is part of the sepsis EGDT bundle?
400
SIRS
What is Systemic Inflamatory Response Syndrome?
400
Decreased blood flow to organ tissue
What is the body's response in sepsis?
400
Leading cause of death in noncoronary ICU (US)
What is severe sepsis and septic shock?
400
Fibrin clots lead to microvascular hypoperfusion, diminished oxygen delivery and tissue necrosis
What is part of the body's response in sepsis?
400
For a lactate >4, the time the result is reported by the lab
What is TIME ZERO?
500
Burns, trauma, pancreatitis
What are SIRS with no evidence of infection?
500
Fibrin clots lead to microvascular hypoperfusion, diminished oxygen delivery and tissue necrosis
What is septic shock?
500
Increases mortality from septic shock by 7%
What is each hour delay in giving antibiotics?
500
Lactate >4
What is an indication of severe sepsis requiring EGDT?
500
The first six hours from TIME ZERO
What are "The Magic Hours"?
M
e
n
u