What's In a Name
SIRS
What is Systemic Inflammatory Response Syndrome?
Altered level of consciousness
What is a possible sign/symptom of sepsis?
210,000 annually
What are the number of deaths from sepsis?
Assessment done for all patients that come to the ER
What is the sepsis screen?
Preassembled set of provider orders for sepsis
What is the Sepsis Orderset?
Body temperature >101F or <96.8F, Heart rate >90 beats per minute, Respiratory rate>20 bpm or PaCO2<32mmHg, WBC <4k or >12k or Bands>10%
What is SIRS criteria?
Alcoholics, untreated GI disease, the elderly
What is who is at higher risk for Sepsis?
Lactate >4
What is an indication of severe sepsis requiring a repeat lactate test in 6 hours?
Known or suspected infection and 2 or more SIRS criteria
What is Sepsis?
Gram Negative Bacteria, Gram Positive Bacteria, Fungi, Viruses
What are the causative microorganisms of sepsis?
25-50%
What is the mortality rate from severe sepsis?
Procedure done prior to administration of antibiotics
What is obtaining blood cultures?
Start an antibiotic within 1 hour
What is required to pass sepsis protocol?
Sepsis + new organ dysfunction
What is Severe Sepsis?
Leading cause of death in noncardiac ICUs (US)
What is severe sepsis?
Procedure done prior to administration of antibiotics
What is obtaining blood cultures?
MODS
What is Multiple Organ Dysfunction?
Fibrin clots cause microvascular hypoperfusion, diminished oxygen delivery, tissue necrosis, and organ failure
What is the cause of death from sepsis?
Increased mortality from severe sepsis by 7%
What is each hour delay in giving antibiotics?