Pathophysiology
The body's overactive and toxic response to an infection.
What is sepsis?
The first intervention to treat hypotension in a patient with sepsis
What is starting 30mL/kg of LR?
This number represents the nationwide mortality rate for sepsis.
What is 30-50%?
An infection more frequently in women that causes confusion.
What is urinary tract infection?
Acuity of ED patient with positive sepsis screen
Positive screen but hemodynamically stable: 2
Positive screen and hemodynamically unstable (hypotension, altered): 1
Name 3 examples of SIRS (Per CMS criteria)
A lab indicator for inadequate tissue perfusion
What is lactic acid?
This percentage of patients are readmitted to the hospital within 90 days after being discharged with sepsis?
What is 33%?
3 types of infections that are the most common causes for sepsis.
What is Pneumonia, UTI, wounds/cellulitis?
Included in the triage suspected sepsis order set
What is bloodwork, urine sample and culture, blood cultures, chest X-ray, LR bolus if hypotensive
Lactic acid >4 or persistent hypotension following fluid bolus.
What is septic shock?
Initial lactic acid was over 2, the next lactic acid be drawn at this time.
What is within 3 hours/after fluid bolus?
The best way to help people with sepsis - name 3
What is early identification, education, prevention? "PIE"
The use of this device is the most common cause for urosepsis?
What is a Foley catheter?
Time sepsis is recognized
What is time zero?
These are signs of infection or put patients at high risk for infection (name 5)
-New cough, urinary symptoms, nausea/vomiting, fever, obvious infection, recent hospitalization, indwelling ports, catheters, lines, recent invasive procedure, antibiotic therapy for infection, immunocompromised
This should be collected prior to antibiotic administration.
What are blood cultures?
Each hour delay in starting antibiotics
What increases mortality from septic shock by 8%?
High risk conditions for sepsis include - name 5
60+, chemo/cancer, immunocompromised, diabetic, liver disease, kidney disease, recent surgery, invasive line, urinary catheter, current/recent hospitalization
Scrub site with chloraprep x 30 sec, let dry 30 sec, do not repalpate, 2 sets 2 sites, do not draw from existing line
What is the method for obtaining blood cultures?
The number one organ failure found in sepsis
What is kidney failure?
Antibiotics should be administered within this time period after sepsis recognition.
What should occur within one hour?
This diagnosis causes more deaths than prostate cancer, breast cancer and AIDS combined. Over 1.5 million diagnosed with this each year and 250,000 die from it.
What is SEPSIS? It's a silent killer.
The type of infections that can lead to sepsis.
What are Bacterial, Viral, and Fungal infections?
Resources for Sepsis
What is --- Up To Date, Sepsis Institute, Sepsis Alliance, Surviving Sepsis Campaign