SIRS
Temperature >100.9 or <96.8 and Respirations >20
What are two SIRS criteria?
2 or more SIRS criteria and a known or suspected infection
What is Sepsis?
350,000
What are the number of deaths annually from sepsis in the U.S.?
Hypoperfusion
What is the main problem in sepsis?
Evidence based set of sepsis interventions
What is the SEP-1 bundle?
Heart Rate >90 and WBC >12,000 or <4,000
What are two SIRS criteria
The elderly, the very young, immunocompromised patients, those with wounds, those with tubes or drains
What is who is at risk for Sepsis?
1.7 million people
What is the amount of people who develop sepsis each year in the US?
Bacterial, viral, or fungal infection
What type of infection leads to sepsis?
Treatment goal for antibiotics in sepsis?
What is less than one hour?
CBC, CMP, Latic Acid, Blood Cultures x2
What are the lab tests used to identify Sepsis?
Required prior to antibiotic administration
What are blood cultures x2?
25-50%
What is the mortality from severe sepsis and septic shock?
Severe Sepsis + Hypotension OR a Lactic Acid of 4.0 or greater
What is septic shock?
Fluid resuscitation amount using LR or NS
What is 30ml/kg?
SIRS
What is Systemic Inflammatory Response Syndrome?
Decreased blood flow to organ tissue
What is hypoperfusion
Leading cause of death in US hospitals
What is Sepsis?
Sepsis + Organ failure
What is severe sepsis?
Preferred IV pressor to treat persistent hypotension
What is levophed?
Two criteria to improve survival chances.
What is early antibiotic and fluid administration?
An infection can be known or "this" to have sepsis.
What is suspected
Increases mortality from severe sepsis by 8%
What is each hour delay in giving antibiotics?
Lactic Acid 4.0 or greater OR hypotension
What is an indication of septic shock?
What is the ultimate goal in sepsis treatment
What is early recognition and early treatment to stop the progression of sepsis to increase survival?