Pathophysiology
This life-threatening condition occurs when the body's response to infection causes widespread inflammation, leading to tissue damage and organ failure.
What is sepsis?
The first intervention to treat hypotension in a patient with sepsis
What is starting 30mL/kg of NS or LR
This temperature range is considered abnormal and may be an early sign of sepsis.
What is >100.4°F or <96.8°F?
An infection more frequently in women that causes confusion.
What is urinary tract infection?
Time sepsis is recognized
What is time zero?
What are examples of SIRS (per CMS criteria)
A lab indicator for inadequate tissue perfusion
What is lactic acid?
This clinical presentation includes hypotension that persists after fluid resuscitation.
What is septic shock?
3 types of infections that are the most common causes for sepsis.
What is Pneumonia, UTI, wounds/cellulitis?
Acuity of ED patient with positive sepsis screen, but hemodynamically stable
What is ESI 2?
What stage of sepsis is a lactic acid >4 or persistent hypotension following fluid bolus?
What is septic shock?
Initial lactic acid was over 2, the next lactic acid be drawn at this time.
What is within 3 hours/after fluid bolus?
The best way to help people with sepsis
What is early identification, education, prevention?
The use of this device is the most common cause for urosepsis?
What is a Foley catheter?
Acuity of ED patient with positive sepsis screen, but hemodynamically unstable (hypotension, altered)
What is ESI 1?
Signs of suspected infection or put patients at high risk for infection
What is new cough, urinary symptoms, nausea/vomiting, fever, obvious infection, recent hospitalization, indwelling ports, catheters, lines, recent invasive procedure, antibiotic therapy for infection, immunocompromised
This should be collected prior to antibiotic administration.
What are blood cultures?
The “M” in TIME highlights this symptom, often described as severe or unbearable.
What is Mental decline or extreme pain?
60+, chemo/cancer, immunocompromised, diabetic, liver disease, kidney disease, recent surgery, invasive line, urinary catheter, current/recent hospitalization
What are high risk conditions for sepsis
Ordered after a positive Sepsis Screen in the ED
What is the Nurse Panel?
This organ is most commonly affected by sepsis-related failure.
What is the kidney?
This is the recommended timeframe for administering antibiotics after recognizing sepsis to improve survival chances.
What is within one hour?
The “E” in TIME stands for this physical sign, often seen as pale, cold, or mottled skin.
What is Extremely ill appearance?
Both bacterial infections, such as those caused by E. coli or Staphylococcus, and viral infections like the flu, can lead to sepsis when they spread throughout the body. (True or False)
True
Resources for Sepsis
Sepsis Alliance
Up To Date
Melinda Wilhite