Pathophysiology
The body's overactive and toxic response to an infection.
What is sepsis?
The first intervention to treat hypotension in a patient with sepsis
What is starting 30mL/kg of LR?
This number represents the nationwide mortality rate for sepsis.
What is 30-50%?
An infection more frequently in women that may also cause confusion along with urinary tract symptoms.
What is a urinary tract infection?
This national campaign provides guidelines and educational tools to help hospitals reduce mortality from sepsis through evidence-based "bundles."
What is the Surviving Sepsis Campaign?
In 1990, this beloved puppeteer and creator of the Muppets tragically died of sepsis caused by a severe bacterial pneumonia.
Who is Jim Henson?
Name 3 examples of SIRS (Per CMS criteria)
A lab indicator for inadequate tissue perfusion
What is lactic acid?
This percentage of patients are readmitted to the hospital within 90 days after being discharged with sepsis?
What is 33%?
3 types of infections that are the most common causes for sepsis.
What is Pneumonia, UTI, wounds/cellulitis?
Name at least 2 orders included in the Sepsis Order Set.
What is bloodwork, urine sample and culture, blood cultures, chest X-ray, LR bolus if hypotensive
In the TV series House, M.D., Dr. House often diagnosed rare causes of sepsis. One memorable case involved this common pet transmitting Capnocytophaga canimorsus after a bite.
What is a dog?
Lactic acid >4 or persistent hypotension following fluid bolus?
What is septic shock
Initial lactic acid was over 2, the next lactic acid be drawn at this time.
What is within 3 hours/after fluid bolus?
According to the CDC, about this percentage of adult sepsis cases begin outside the hospital setting.
What is 87%?
The use of this device is the most common cause for urosepsis?
What is a Foley catheter?
Time sepsis is recognized
What is time zero?
In the movie Million Dollar Baby (2004), Hilary Swank’s character develops sepsis from complications of these hospital-acquired wounds.
What are pressure ulcers (bedsores)?
This imbalance of pro-coagulant and anti-coagulant pathways in sepsis can progress to widespread microvascular thrombosis and consumption of clotting factors.
What is disseminated intravascular coagulation (DIC)?
This should be collected prior to antibiotic administration.
What are blood cultures?
Mortality from septic shock increases by what percent with each hour delay in starting antibiotics.
What is 8%
Name at least 2 high risk conditions or risk factors for sepsis.
60+, chemo/cancer, immunocompromised, diabetic, liver disease, kidney disease, recent surgery, invasive line, urinary catheter, current/recent hospitalization
Scrub site with chloraprep x 30 sec, let dry 30 sec, do not repalpate, 2 sets 2 sites, do not draw from existing line
What is the method for obtaining blood cultures?
In 2013, this world leader was hospitalized with recurrent lung infections and sepsis, ultimately contributing to his death at age 95.
Who is Nelson Mandela?
The number one organ failure found in sepsis
What is kidney failure?
Antibiotics should be administered within this time period after sepsis recognition.
What should occur within one hour?
This diagnosis causes more deaths than prostate cancer, breast cancer and AIDS combined. Over 1.5 million diagnosed with this each year and 250,000 die from it.
What is SEPSIS? It's a silent killer.
This encapsulated organism, a leader cause of sepsis in asplenic patients, can also present with pneumonia or meningitis.
What is Streptococcus pneumoniae?
Resources for Sepsis
Jessica Baker
Elsevier
Up To Date
Sepsis Institute
Sepsis Alliance
In 2003, following his fourth surgery on his left ankle, this NBA Hall of Famer contracted a severe, life-threatening MRSA infection.
Who is Grant Hill?