Two Generals
Sepsis
Sepsis Stats
Septic Tank
Treatment
100

Temperature >38 C and Respirations > 20

What are two SIRS criteria?

100

Known or suspected bacterial infection and 2 or more SIRS criteria

What is Sepsis?

100
210,000
What are the number of deaths annually from sepsis?
100
Perfusion
What is the main problem in sepsis?
100

Evidence based set of sepsis interventions

What is Sepsis Treatment Algorithm/Order Sets?

200

Heart rate > 90 and WBC >12,000 or >10% bands

What are two SIRS criteria?

200

Alcoholics, untreated GI disease, the elderly

Who is at risk for Sepsis?

200
10th
What is the ranking of sepsis deaths compared to other deaths in the US?
200

Bacterial, Viral or Fungal Infection

What type of infection leads to sepsis?

200

Start a broad spectrum antibiotic within 3 hours

What is a treatment goal of the Sepsis Treatment Algorithm/Order Set?

300

CMP, Lactic Acid, Blood Cultures X 2

What are lab tests used to identify Sepsis?

300

 Required prior to antibiotic administration

What are blood cultures x 2?

300
25-50%
What is the mortality from severe sepsis and septic shock?
300

2 or more SIRS Criteria plus suspected bacterial infection

How many SIRS criteria are necessary to diagnosis Sepsis?

300

Fluid Resuscitation amount using LR or NS

What is 30ml/kg?

400
SIRS
What is Systemic Inflamatory Response Syndrome?
400

Decreased blood flow to organ tissue

What is the body's response in sepsis?

400
Leading cause of death in noncoronary ICU (US)
What is severe sepsis and septic shock?
400

Sepsis + Organ Failure

What is severe sepsis?

400

Preferred IV pressor to treat persistent hypotension

What is Levophed?

500

Two interventions to improve survival chances

What are large amounts of IV fluids and early treatment with antibiotics?

500

Fibrin clots lead to microvascular hypoperfusion, diminished oxygen delivery and tissue necrosis

What is septic shock?

500
Increases mortality from septic shock by 7%
What is each hour delay in giving antibiotics?
500

Lactic Acid > or =4

What is an indication of septic shock?

500

Broad Spectrum Antibiotics given to treat Sepsis

What are Ceftriaxone, Ceftazidime, Cefepime, Ampicillin/sulbactam, Piperacillin/tazobactam, or Levofloxin?

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