Identification
Vitals indicating Sepsis
What is fever, tachycardia, elevated respiration rate and hypotension?
Newborns, the elderly, pregnant women, individuals with a comprimised immune system, chronic disease, extended hospitals stays and invasive devices.
Who is at an increased risk for Sepsis?
SIRS
What is Systemic Inflamatory Response Syndrome?
Drawn before antibiotic administration.
What is Blood Cultures x2?
Start a broad spectrum antibiotic within 3 hours
What is the treatment goal of the 3 hour bundle?
2 or more SIRS Criteria plus suspected bacterial infection
How many SIRS criteria are necessary to diagnosis Sepsis?
Bacterial, Viral or Fungal Infection
What type of infection leads to sepsis?
Decreased blood flow to organ tissue
What is the body's response in sepsis
Lab tests used to identify Sepsis
What is CMP, Lactic Acid, and Blood Cultures x2
Fluid Resuscitation amount using LR or NS
What is 30ml/kg?
Mortality from sepsis increases by as much as 8% for every hour that treatment is delayed. As many as 80% of sepsis deaths could be prevented with
What is rapid diagnosis and treatment?
Time frame for sepsis bundle
What is within 3 hours of time zero?
Leading cause of death in U.S. hospitals and the leading cause of readmissions
What is Sepsis?
Lactic Acid > or =4
What is an indication of Septic Shock
Preferred IV pressor to treat persistent hypotension
What is Levophed?
Represents a modified Sepsis alert that is meant to capture high-risk patients
What is a SAFE Alert
25-50%
What is the mortality from severe sepsis and septic shock?
Sepsis + Organ Failure
What is severe sepsis?
System will fire a re-draw after an elevated Lactic acid at what interval?
What is 3 Hours?
Assessed after administration of fluid resuscitation
What is vital signs, cap refill, peripheral pulses, auscultation of heart and lung sounds
What is Time Zero?
Increases mortality from septic shock by 8%
What is each hour delay in giving antibiotics?
Hypovolemia, hypoxia and maldistribution of blood flow lead to cellular hypoperfusion. As the cells become starved for oxygen they switch over to what type of metabolism?
What is anaerobic metabolism? *bonus: cells are unable to perform their functions efficiently leading organ dysfunction
Elevated in a patient with Sepsis
What is WBC and Lactic?
Broad Spectrum Antibiotics given to treat Sepsis
What are Ceftriaxone, Ceftazidime, Cefepime, Ampicillin/sulbactam, Piperacillin/tazobactam, or Levofloxin?