SIRS
What is Systemic Inflammatory Response Syndrome?
Altered level of consciousness
What is a possible sign/symptom of sepsis?
210,000 annually
What are the number of deaths from sepsis?
Assessment done for all patients that come to the ER
What is the Sepsis Screening?
Preassembled set of provider orders for sepsis
What is the Sepsis Orderset?
Body temperature >101F or <96.8F, Heart rate >90 beats per minute, Respiratory rate>20 bpm or PaCO2<32mmHg, WBC <4k or >12k or Bands>10%
What is SIRS criteria?
Alcoholics, untreated GI disease, the elderly
What is who is at higher risk for Sepsis?
10th
What is the ranking of sepsis deaths compared to other deaths in the US?
Lactate >2
What is an indication of organ dysfunction?
IVs times two
What is the minimum of IV access for a patient with suspected Sepsis?
Known or suspected infection and 2 or more SIRS criteria
What is Sepsis?
Gram Negative Bacteria, Gram positive Bacteria, Fungi, Viruses
What are the causative microorganisms of sepsis?
25-50%
What is the mortality rate from severe sepsis?
Repeat lactate
What is required in 6 hours if lactate is >2?
Antibiotic started within 1 hour
What is required to pass CMS sepsis criteria?
Sepsis + new organ dysfunction
What is Severe Sepsis?
Decreased blood flow to organ tissue
What is the body’s response to sepsis?
Leading cause of death in non-cardiac ICUs (US)
What is Severe Sepsis?
Timeframe for completing the second Sepsis assessment
What is 2 hours?
If antibiotics are given prior to blood cultures being drawn
What is document the reason antibiotics where given before cultures were drawn?
MODS
What is Multiple Organ Dysfunction?
Fibrin clots cause microvascular hypoperfusion, diminished oxygen delivery, tissue necrosis, and organ failure
What is the cause of death from sepsis?
Increased mortality from severe sepsis by 7%
What is each hour of delay in giving antibiotics?
Procedure ideally done prior to administration of antibiotics
What is obtaining blood cultures?
Order of antibiotics given, if more than one type is ordered
What is give the broad spectrum antibiotic first?