Sickle-Cell 1
What causes Sickle Cell Disease/Anemia?
an inherited genetic mutation that affects the hemoglobin.
Sickle Cell anemia is believed to be a genetic mutation that evolved years ago as a protection against this.
What is Malaria?
This, also called sickle cell crisis, is a common painful complication of sickle cell disease in adolescents and adults.
What is the Vaso-occlusive crisis?
What is Sickle Cell trait?
The great majority of people living with sickle cell disease in the U.S. are of African descent, but this ethnicity group make up the second largest group affected by sickle cell disease
What are Latinos?
The protein that makes fetal hemoglobin is
What is gamma-globin gene
How many copies of the sickle cell gene must a child have to be affected?
Two (one from the mother and one from the father)
Vaso-occlusion is responsible for a wide variety of clinical complications of sickle cell disease, including these.
What are pain syndromes, stroke, leg ulcers, spontaneous abortion or renal insufficiency?
This potentially life-saving procedure can help replace blood lost due to surgery or injury.
What is a blood transfusion?
This month was proclaimed Sickle cell awareness month in Buffalo and WNY by Mayor Byron Brown.
What is the month of September?
An abnormal form of hemoglobin that makes red blood cells rigid and sickle-shaped?
What is Hemoglobin S?
What does hemoglobin do?
Enables red blood cells to carry oxygen from the lungs throughout the body
Of the four primary SCD genotypes, these two types tend to be the most clinically severe forms of the disease and are collectively termed sickle cell anemia (SCA).
What is HbSS and HbSβ0-thalassemia
What are blood donations?
A one-time gene therapy to treat sickle cell disease in individuals 12 years of age or older and a history of Vaso-occlusive events (VOEs).
What is LYFGENIA?
What does RNA stand for?
Ribonucleic Acid
What is being a carrier of the Sickle Cell gene?
What is Sickle Cell trait?
The death of bone tissue due to lack of blood supply.
What is Avascular necrosis (a bone infarction)?
It is critical to have to have this type of group of blood donors to help all patients in need
What are diverse blood donors?
1 in 2 African Americans with this blood type are a match for Sickle Cell patients while only 1 in 40 of this blood type of other ethnicities.
What is blood type O?
What is Sickle Cell Anemia?
What happens to the shape of the blood cells?
They become sickle-shaped.
These kinds of scans can be done to reveal areas of bone destruction and sclerosis indicating bone infarction.
What are MRI scans and X-rays?
Sickle cell patients are more likely to find this from a donor of the same race or ethnic group.
What is a compatible blood match?
Individuals with Sickle Cell need an average of this many blood transfusions per year or more, depending on the severity.
What is 15-25 blood transfusions?