What Is the Mechanism of action of metformin in lowering blood sugar
Primarily reduces hepatic gluconeogenesis; also increases peripheral insulin sensitivity and decreases intestinal glucose absorption
My favourite company
Apple
Capital city of australia
Canberra
In K-POP demon Hunters what is the name of the K-pop girl group the main characters are a part of
Hunter/x
Largest animal in the word
The blue whale
A patient has hyponatraemia with high urine osmolality and high urine sodium, euvolaemic on exam, with normal thyroid and adrenal function. What is the diagnosis?
SIADH
(Syndrome of Inappropriate Antidiuretic Hormone secretion)
My favourite country
England
What colour do you get when red and white paint are mixed
pink
In Star Wars,A new hope what color is Luke Skywalker’s lightsaber
Blue
A dog that doesn’t bark
Husky
A 52-year-old woman presents with progressive proximal muscle weakness, a heliotrope rash around the eyes, and Gottron’s papules over the knuckles. CK is elevated. What is the diagnosis, and what malignancy screening is particularly important in this age group?
Dermatomyositis; screen for ovarian, lung, pancreatic, gastric, and colorectal malignancy — dermatomyositis has a strong paraneoplastic association, especially in patients over 40)
What is my favourite chocolate brand Bonus points for flavour
Tony‘S chocoloney salted caramel
Which two countries share the longest international land border in the world?
Canada and US
In Rambo first blood what war is Rambo a veteran of
The vietnam war
This breed of dog, known for its incredible sense of smell, is most commonly used by police and the military for detection work.
The german Shepard
A 60-year-old man on long-term phenytoin develops fever, a diffuse rash, facial oedema, lymphadenopathy, and eosinophilia 3 weeks after starting the drug. LFTs are deranged. What is this syndrome, what is the proposed underlying immunological mechanism, and why is the latency period clinically significant?
DRESS syndrome — Drug Reaction with Eosinophilia and Systemic Symptoms; thought to involve HHV-6 reactivation alongside a delayed T-cell-mediated hypersensitivity reaction; the 2–8 week latency distinguishes it from typical immediate drug hypersensitivity and is a key diagnostic clue, often missed because the causative drug has long been considered “tolerated” by that point)
Favourite car brand
What is the name of the only letter in the English alphabet that does not appear in the name of any element on the periodic table?
J
In Braveheart, what real historical Scottish figure does Mel Gibson’s character represent?
William Wallace
Most likely animal to kill you based on stats in australia
a horse most of them is from getting kicked or thrown off
A patient with a midgut neuroendocrine tumour and confirmed liver metastases has biochemically elevated chromogranin A and 5-HIAA, yet is entirely asymptomatic at rest, only flushing under specific triggers, with no diarrhoea but prominent bronchospasm. What rare tumour secretory profile explains this atypical phenotype, what alternate vasoactive mediators are implicated instead of serotonin, and what enzymatic deficiency in these tumours’ biosynthetic pathway accounts for the shift?
(These represent foregut/gastric-type carcinoids with reduced or absent aromatic L-amino acid decarboxylase activity, impairing conversion of 5-HTP to serotonin; precursor metabolism is shunted toward histamine and tachykinins — substance P and neurokinin A — producing a histamine-predominant phenotype with flushing and bronchospasm but minimal serotonin-driven diarrhoea, and detectable via elevated urinary methylimidazoleacetic acid rather than the classical 5-HIAA elevation alone)
My favourite element
Gallium
Only US state that borders only 1 other state
Maine—borders new hampshire
This 1995 Pixar film was the first feature-length film made entirely with computer animation.
Toy story
Japan’s Shinkansen 500 series bullet train was redesigned with a long, narrow nose to reduce noise and improve speed, directly inspired by this bird’s beak shape
Kingfisher