Malignant Minds
Tumor markers to assess poorly differentiated CUP with mediastinal adenopathy (cancer of unknown primary (CUP))
α-fetoprotein and β-HCG
Treatment for severe COPD
Triple inhaler therapy with LABA, LAMA, inhaled glucocorticoid
Confirmatory test for HIT when EIA is positive
Serotonin release or heparin-induced platelet aggregation assay
Pink, scaly indurated plaque skin cancer
Squamous cell carcinoma
Peripheral neuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, skin changes
POEMS syndrome : POEMS syndrome (Polyneuropathy, Organomegaly, Endocrinopathy, Monoclonal plasma cell disorder, Skin changes) is a paraneoplastic process characterized by the presence of a monoclonal plasma cell disorder, peripheral neuropathy, and other features.
Chemotherapeutic agents causing hand-foot syndrome
5-FU and capecitabine
Carboxyhemoglobin level indication for hyperbaric therapy
>25%
Treatment of SCD with frequent pain events, severe symptomatic anemia, previous ACS, or stroke
Hydroxyurea
Sexually transmitted umbilicated flesh-colored papules
Molluscum contagiosum
Diagnosis suggested by dementia, apathy, disinhibition, changes in eating behaviors, hyperorality, compulsiveness
Behavioral-variant frontotemporal dementia
Treatment of oligometastatic colorectal cancer
Surgical resection
Diagnosis suggested by CNS depression, increased osmolar gap, normal anion gap
Isopropyl alcohol ingestion
Eosinophilia and end-organ damage
HES:Hypereosinophilic syndrome (HES) is a rare group of disorders that involve a sustained increase in eosinophils in the blood. This can lead to damage to organs like the heart, lungs, skin, and nervous system.
Nail findings of psoriasis
Pitting, onycholysis, “oil spots,” nail plate thickening
Red flags for secondary headache
Focal neurologic findings, worst/progressive headache, new headache after age 50 years, thunderclap headache, onset after exertion.
Prevention of BRCA-mutation ovarian cancer
Bilateral salpingo-oophorectomy
Systemic sclerosis variant associated with PAH
Limited cutaneous systemic sclerosis
PCD with monoclonal protein exceeding limit for MGUS, no other symptoms, no end-organ damage
Smoldering myeloma
Pigmented macule with a surrounding hypopigmentation
Halo nevus
Treatment for post–dural-puncture headache
Epidural blood patch
Antibody that potentiates metastatic colon cancer chemotherapy
Bevacizumab
Diagnosis suggested by TLC <80% of predicted
Restrictive lung disease
Initial treatment of chronic-phase CML
Tyrosine kinase inhibitor
Risk associated with multiple dysplastic nevi
Melanoma
Seizure, tunnel vision, <1 min loss of consciousness, immediate recovery
Convulsive syncope