Vocabulary & Structure
Bone Cells & Remodeling
Bone Matrix & Mineralization
Calcium Homeostasis
Bone Growth & Ossification
100

this is a bone-building cell

osteoblast

100

why is compact bone organized into osteons?

osteons organize compact bone around blood vessels and increase strength 

100

what is bone matrix composed of?

proteins and minerals

100

which hormone increases blood calcium?

parathyroid hormone

100

which process forms most long bones?

endochondral ossification

200

this is a bone-resorbing/breaking cell

osteoclast

200

why does spongy bone contain many open spaces?

reduces weight and allows space for marrow

200

why is collagen important to bone tissue?

provides flexibility and tensile strength 

200

which hormone promotes calcium deposition into bone?

calcitonin

200

this form of ossification develops bone directly from connective tissue

intramembranous ossification

300

this is a mature bone cell that maintains bone tissue 

osteocyte 

300

what would happen if osteoclast activity greatly exceeded osteoblast activity?

decreased bone strength and density

300

why is calcium phosphate important in bone tissue?

provides hardness and compression resistance 

300

this is the active form of vitamin D

calcitriol

300

this form of ossification involves bone replacing cartilage 

endochondral ossification

400

this is the structural unit of compact bone

osteon

400

what would happen if bone remodeling stopped completely?

bones could weaken and calcium balance would be disrupted

400

why are both collagen and minerals necessary in bone?

bone requires flexibility and hardness for proper function

400

how does calcitriol help maintain calcium homeostasis?

increases calcium absorption from the digestive system

400

this is the site of longitudinal bone growth

epiphyseal plate 

500

this is the lattice-like structure in spongy bone

trabeculae

500
why must bone remodeling remain balanced?
too much breakdown- weakened bone, too much deposition- alter normal structure
500

how does the bone matrix demonstrate the structure-function relationship?

collagen provides flexibility while minerals provide strength 

500

what would happen if blood calcium levels decreased significantly?

muscle/nervous dysfunction may occur, parathyroid hormone may be released 

500

what would happen if the epiphyseal plate closed early?

bone growth/height would stop early

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